STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpC-2PFAM: Indole-3-glycerol phosphate synthase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR001468:IPR013798; KEGG: npu:Npun_R1265 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (287 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpF
PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: npu:Npun_F1706 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 0.999
Chro_3140
PFAM: Glutamine amidotransferase class-I; chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; anthranilate synthase, alpha proteobacterial clade; COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterProIPR006805:IPR015890:IPR000991:IPR010112:IPR 017926:IPR006221:IPR006220:IPR011702; KEGG: npu:Npun_R1266 anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; glutamine amidotransferase class-I; SPT [...]
 
 0.999
trpB-2
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 0.997
trpA-2
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 0.995
Chro_5567
PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR017926:IPR006221:IPR006220:IPR011702:IPR 001317:IPR000991; KEGG: npu:Npun_F1347 glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; SPTR: Glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase.
  
 0.993
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.987
Chro_3145
PFAM: Glycosyl transferase family, a/b domain; TIGRFAM: anthranilate phosphoribosyltransferase; COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR000312:IPR005940; KEGG: msv:Mesil_0337 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase.
  
 0.987
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
 
 0.982
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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