STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
Chro_3351Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR013656:IPR003661:IPR003594:IPR005467:IPR 000014:IPR004358; KEGG: npu:Npun_F3675 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine k [...] (525 aa)    
Predicted Functional Partners:
Chro_3352
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR003661:IPR003594:IPR 005467:IPR000014:IPR000700:IPR001610:IPR004358; KEGG: cyn:Cyan7425_3771 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinas [...]
 
 
0.967
Chro_4846
PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR016132:IPR005467:IPR001789:IPR000014:IPR 000700:IPR004358:IPR013656:IPR003018:IPR013655:IPR003661:I PR003594:IPR001610; KEGG: npu:Npun_R4748 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; respon [...]
 
0.962
Chro_2201
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR005467:IPR001789:IPR000014:IPR 000700:IPR003661:IPR003594:IPR013656; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: response regulator receiver; A [...]
 
 
0.956
Chro_4459
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR001610:IPR003661:IPR003594:IPR 005467:IPR000014:IPR000700:IPR004358:IPR013655; KEGG: cyn:Cyan7425_3771 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinas [...]
 
0.956
Chro_1592
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 001610:IPR003661:IPR003594:IPR004358:IPR013767; KEGG: npu:Npun_R2901 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATP [...]
 
0.955
Chro_4923
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR003660:IPR004358:IPR 003018:IPR003661:IPR003594:IPR018062; KEGG: cyn:Cyan7425_3768 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region [...]
  
 
0.954
Chro_5133
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467; KEGG: amr:AM1_5975 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine [...]
 
 
0.952
Chro_3030
ATP-binding region ATPase domain protein; PFAM: Protein kinase domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG3899 ATPase; InterProIPR017442:IPR003018:IPR003661:IPR003594:IPR 001789:IPR020635:IPR002290:IPR000719:IPR005467:IPR002160:I PR004358; KEGG: cyn:Cyan7425_0791 ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; Serine/threonine-protein kinase-like domain; response regulator r [...]
 
 
0.950
Chro_0657
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR004358:IPR003018:IPR 003661:IPR003594; KEGG: cyt:cce_0164 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain prot [...]
 
 
0.949
Chro_5472
PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR000014:IPR001610:IPR003661:IPR 003594:IPR001789:IPR005467:IPR000700:IPR004358:IPR013767; KEGG: ana:alr1968 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region [...]
 
0.948
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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