Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Chro_3370PFAM: Single-strand binding protein family; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: cyn:Cyan7425_1502 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein. (160 aa)    
Predicted Functional Partners:
priA
Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
 
 
 0.855
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.822
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
    0.756
Chro_5267
Intein; PFAM: OB-fold nucleic acid binding domain; TIGRFAM: intein C-terminal splicing region; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004365:IPR006141; KEGG: ava:Ava_3748 DNA polymerase III subunit alpha; PFAM: nucleic acid binding OB-fold tRNA/helicase-type; SPTR: DNA polymerase III, alpha subunit / Intein.
 
 
 
 0.721
Chro_2668
KEGG: ava:Ava_0665 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.708
Chro_5269
PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR004805:IPR006141:IPR 003141:IPR003587; KEGG: ana:all3578 DNA polymerase III subunit alpha; PFAM: DNA polymerase III alpha subunit; PHP domain protein; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; Hedgehog/intein hint domain protein; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit.
 
 
 
 0.696
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.672
rpsB
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; COGs: COG0052 Ribosomal protein S2; InterPro IPR018130:IPR020053:IPR001865:IPR005706; KEGG: naz:Aazo_4883 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: Ribosomal protein S2; TIGRFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
  0.669
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.668
rplJ
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
    0.660
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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