STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_4792PFAM: Mannose-6-phosphate isomerase; COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR001538; KEGG: ava:Ava_1292 mannose-6-phosphate isomerase type II; PFAM: mannose-6-phosphate isomerase type II; SPTR: Mannose-6-phosphate isomerase, type II. (139 aa)    
Predicted Functional Partners:
Chro_4457
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: npu:Npun_R5110 nucleotidyl transferase; PFAM: Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Nucleotidyl transferase.
     0.974
Chro_3371
Nucleotidyl transferase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR018357:IPR005835:IPR001451:IPR005844; KEGG: npu:Npun_R6155 nucleotidyl transferase [...]
  
 
 0.928
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: npu:Npun_F3925 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.911
fbp
D-fructose 1,6-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146:IPR020548; KEGG: ava:Ava_1680 fructose-1,6-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 1; Belongs to the FBPase class 1 family.
    
  0.906
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.903
Chro_2105
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: npu:Npun_R4240 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein.
    
 0.903
Chro_5171
PFAM: Mannose-6-phosphate isomerase; COGs: COG0662 Mannose-6-phosphate isomerase; InterPro IPR001538; KEGG: ava:Ava_1405 mannose-6-phosphate isomerase type II; PFAM: mannose-6-phosphate isomerase type II; SPTR: Mannose-6-phosphate isomerase, type II.
  
  
 
0.903
Chro_4708
PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase; COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148; KEGG: ana:all0727 glucosamine-6-phosphate deaminase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: Glucosamine-6-P isomerase.
     
 0.901
Chro_5405
Sedoheptulose 1,7-bisphosphatase, D-fructose 1,6-bisphosphatase; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: cyc:PCC7424_5180 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein; PRIAM: Sedoheptulose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase, class II; TIGRFAM: fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.
     
 0.901
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
  0.900
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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