STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_5207PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: npu:Npun_R6581 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; Belongs to the Fur family. (131 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.751
purS
Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...]
       0.589
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
     
 0.582
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.554
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.545
Chro_1383
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479:IPR017936; KEGG: naz:Aazo_4615 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen.
  
  
 0.522
Chro_4479
PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; COGs: COG0450 Peroxiredoxin; InterPro IPR017936:IPR000866:IPR019479; KEGG: amr:AM1_5494 alkyl hydroperoxide reductase/thiol specific antioxidant family protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; PRIAM: Peroxidase; SPTR: Alkyl hydroperoxide reductase/Thiol specific antioxidant family protein.
  
  
 0.522
Chro_2007
Transcriptional regulator; PFAM: HTH domain; TIGRFAM: iron-sulfur cluster biosynthesis transcriptional regulator SufR; COGs: COG2345 transcriptional regulator protein; InterPro IPR014075:IPR001034; KEGG: npu:Npun_R4821 iron-sulfur cluster biosynthesis transcriptional regulator protein SufR; SPTR: Putative uncharacterized protein; TIGRFAM: iron-sulfur cluster biosynthesis transcriptional regulator SufR.
  
    0.441
Chro_2209
PFAM: HTH domain; COGs: COG2345 transcriptional regulator protein; KEGG: ava:Ava_C0028 transcriptional regulator; SPTR: Predicted transcriptional regulator.
  
    0.441
Chro_2824
Transcriptional regulator; TIGRFAM: iron-sulfur cluster biosynthesis transcriptional regulator SufR; COGs: COG2345 transcriptional regulator protein; InterPro IPR014075; KEGG: cyc:PCC7424_3070 transcriptional regulator, TrmB; SPTR: Iron-sulfur cluster biosynthesis transcriptional regulator SufR; TIGRFAM: iron-sulfur cluster biosynthesis transcriptional regulator SufR.
  
    0.441
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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