STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_5297PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: npu:Npun_R4331 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family. (305 aa)    
Predicted Functional Partners:
Chro_5295
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198; KEGG: ent:Ent638_1528 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
       0.539
Chro_5296
Hypothetical protein.
       0.539
Chro_1129
Transcriptional regulator, AraC family; PFAM: AraC-like ligand binding domain; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449:IPR000005:IPR018060:IPR018062; KEGG: mul:MUL_0821 transcriptional regulatory protein; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulatory protein.
  
  
 0.486
menB
1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
       0.474
Chro_3093
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018062:IPR000005:IPR018060:IPR020449; KEGG: ana:all3171 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator.
  
    0.463
Chro_5576
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060:IPR018062:IPR020449:IPR000005; KEGG: cyc:PCC7424_0085 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
  
    0.459
Chro_3612
PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR006058:IPR008333:IPR001433:IPR001041:IPR 017927; KEGG: npu:Npun_F2215 oxidoreductase FAD/NAD(P)-binding subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein.
 
   
 0.418
Chro_3057
Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: cyc:PCC7424_3654 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Large subunit of NADH-dependent glutamate synthase.
  
  
 0.404
Chro_3459
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: ava:Ava_1294 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin).
  
  
 0.404
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.