STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS83523.1Predicted oxidoreductase. (329 aa)    
Predicted Functional Partners:
SIS83539.1
AraC-type DNA-binding protein.
 
     0.555
SIS83491.1
ABC-2 type transport system permease protein.
       0.545
SIS83507.1
ABC-2 type transport system ATP-binding protein.
       0.545
SIS81149.1
Aldo/keto reductase.
 
0.494
SIS79485.1
Peptidyl-prolyl cis-trans isomerase (rotamase)-cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.479
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
   0.410
SIS75110.1
DnaJ domain-containing protein.
    
   0.410
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
   0.400
Your Current Organism:
Alicyclobacillus vulcanalis
NCBI taxonomy Id: 252246
Other names: A. vulcanalis, ATCC BAA-915, Alicyclobacillus vulcanalis Simbahan et al. 2004, Alicyclobacillus vulcanis, DSM 16176, strain CsHg2
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