STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS94717.1Negative transcriptional regulator, PaiB family. (218 aa)    
Predicted Functional Partners:
SIS94702.1
Acyl-coenzyme A thioesterase PaaI, contains HGG motif.
       0.774
hisC-2
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.517
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
       0.494
SIS94764.1
Pyruvate dehydrogenase E1 component beta subunit.
       0.494
SIS94780.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
       0.473
SIS94796.1
Short chain enoyl-CoA hydratase.
       0.459
Your Current Organism:
Alicyclobacillus vulcanalis
NCBI taxonomy Id: 252246
Other names: A. vulcanalis, ATCC BAA-915, Alicyclobacillus vulcanalis Simbahan et al. 2004, Alicyclobacillus vulcanis, DSM 16176, strain CsHg2
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