STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (474 aa)    
Predicted Functional Partners:
gmhA
Sugar isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.998
OOC10281.1
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.984
OOC10278.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.897
OOC10263.1
Sulfotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.689
OOC10225.1
FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.683
kdsA
3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family.
    
 0.657
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
    
 0.646
OOC10261.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.613
OOC08870.1
D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.567
OOC09121.1
Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.566
Your Current Organism:
Thioalkalivibrio halophilus
NCBI taxonomy Id: 252474
Other names: DSM 15791, Thialkalivibrio halophilus, Thioalkalivibrio halophilus corrig. Banciu et al. 2005, UNIQEM U225, strain HL 17
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