PV09_06793 protein (Verruconis gallopava) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PV09_06793

Uncharacterized protein. (387 aa)

Predicted Functional Partners:

PV09_03927

0.994

PV09_00351

0.988

PV09_08163

0.974

PV09_05419

0.974

PV09_09192

0.952

PV09_03048

0.928

PV09_03272

0.928

PV09_07573

0.909

uba4

0.711

PV09_06937

0.673

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00351	PV09_03048	A0A0D1Z921	A0A0D2B3J9	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.875
PV09_00351	PV09_03272	A0A0D1Z921	A0A0D2B4F3	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.875
PV09_00351	PV09_03927	A0A0D1Z921	A0A0D1XRV0	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	0.996
PV09_00351	PV09_05419	A0A0D1Z921	A0A0D2A8V8	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.960
PV09_00351	PV09_06793	A0A0D1Z921	A0A0D1XI55	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.988
PV09_00351	PV09_06937	A0A0D1Z921	A0A0D2ARD8	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.920
PV09_00351	PV09_07573	A0A0D1Z921	A0A0D2APJ2	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Barwin domain-containing protein.	0.844
PV09_00351	PV09_08163	A0A0D1Z921	A0A0D2A0T2	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.984
PV09_00351	PV09_09192	A0A0D1Z921	A0A0D2AJI5	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Uncharacterized protein.	0.875
PV09_00351	uba4	A0A0D1Z921	A0A0D2AR43	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.670
PV09_03048	PV09_00351	A0A0D2B3J9	A0A0D1Z921	Uncharacterized protein.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.875
PV09_03048	PV09_03927	A0A0D2B3J9	A0A0D1XRV0	Uncharacterized protein.	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	0.878
PV09_03048	PV09_05419	A0A0D2B3J9	A0A0D2A8V8	Uncharacterized protein.	Uncharacterized protein.	0.869
PV09_03048	PV09_06793	A0A0D2B3J9	A0A0D1XI55	Uncharacterized protein.	Uncharacterized protein.	0.928
PV09_03048	PV09_06937	A0A0D2B3J9	A0A0D2ARD8	Uncharacterized protein.	Uncharacterized protein.	0.559
PV09_03048	PV09_08163	A0A0D2B3J9	A0A0D2A0T2	Uncharacterized protein.	Uncharacterized protein.	0.867
PV09_03272	PV09_00351	A0A0D2B4F3	A0A0D1Z921	Uncharacterized protein.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.875
PV09_03272	PV09_03927	A0A0D2B4F3	A0A0D1XRV0	Uncharacterized protein.	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	0.878
PV09_03272	PV09_05419	A0A0D2B4F3	A0A0D2A8V8	Uncharacterized protein.	Uncharacterized protein.	0.869
PV09_03272	PV09_06793	A0A0D2B4F3	A0A0D1XI55	Uncharacterized protein.	Uncharacterized protein.	0.928

page 1 of 5

Network Stats

number of nodes:

9

number of edges:

36

average node degree:

8

avg. local clustering coefficient:

1

expected number of edges:

8

PPI enrichment p-value:

8.16e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007035

Vacuolar acidification

2 of 19

2.55

1.22

0.0255

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

3 of 22

2.66

3.31

3.64e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016471

Vacuolar proton-transporting V-type ATPase complex

3 of 21

2.68

3.55

1.67e-05

GO:0000220

Vacuolar proton-transporting V-type ATPase, V0 domain

2 of 12

2.75

2.29

0.0010

GO:0000329

Fungal-type vacuole membrane

2 of 73

1.96

1.33

0.0128

GO:0031090

Organelle membrane

4 of 973

1.14

1.0

0.0026

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6446

Proton-transporting V-type ATPase, V1 domain, and V-ATPase proteolipid subunit C, eukaryotic

3 of 12

2.93

3.8

9.91e-06

CL:6449

Proton-transporting V-type ATPase, V1 domain

2 of 7

2.98

2.36

0.00088

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

aalt04145

Phagosome

3 of 33

2.49

3.64

8.55e-06

aalt00190

Oxidative phosphorylation

3 of 73

2.14

2.92

4.20e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-917977

Transferrin endocytosis and recycling

3 of 22

2.66

3.47

2.14e-05

MAP-77387

Insulin receptor recycling

3 of 22

2.66

3.47

2.14e-05

MAP-74752

Signaling by Insulin receptor

3 of 24

2.62

3.45

2.14e-05

MAP-1222556

ROS and RNS production in phagocytes

3 of 24

2.62

3.45

2.14e-05

MAP-9639288

Amino acids regulate mTORC1

3 of 42

2.38

3.25

2.64e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033176

Proton-transporting V-type ATPase complex

2 of 16

2.62

1.52

0.0102

GOCC:0005773

Vacuole

3 of 187

1.73

1.3

0.0102

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

3 of 15

2.83

4.28

1.96e-06

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About