PV09_01652 protein (Verruconis gallopava) - STRING interaction network

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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PV09_01652

Peptidase S53 domain-containing protein. (637 aa)

Predicted Functional Partners:

PV09_02086

0.569

PV09_00248

0.507

PV09_05856

0.498

PV09_03921

0.490

PV09_02189

0.489

PV09_05611

0.485

PV09_03514

0.480

PV09_06563

0.474

PV09_08988

0.470

PV09_01342

0.470

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00248	PV09_01652	A0A0D1Z8K3	A0A0D1XY27	26S proteasome regulatory subunit rpn11.	Peptidase S53 domain-containing protein.	0.507
PV09_00248	PV09_02086	A0A0D1Z8K3	A0A0D2B7J9	26S proteasome regulatory subunit rpn11.	Uncharacterized protein.	0.496
PV09_00248	PV09_03921	A0A0D1Z8K3	A0A0D2AEI7	26S proteasome regulatory subunit rpn11.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.684
PV09_00248	PV09_05611	A0A0D1Z8K3	A0A0D1XLW6	26S proteasome regulatory subunit rpn11.	Ubiquitin-like domain-containing protein.	0.769
PV09_00248	PV09_06563	A0A0D1Z8K3	A0A0D2A5S2	26S proteasome regulatory subunit rpn11.	Polyubiquitin.	0.995
PV09_01342	PV09_01652	A0A0D2BAX2	A0A0D1XY27	Allophanate hydrolase.	Peptidase S53 domain-containing protein.	0.470
PV09_01342	PV09_08988	A0A0D2BAX2	A0A0D2AK35	Allophanate hydrolase.	Urea carboxylase.	0.977
PV09_01652	PV09_00248	A0A0D1XY27	A0A0D1Z8K3	Peptidase S53 domain-containing protein.	26S proteasome regulatory subunit rpn11.	0.507
PV09_01652	PV09_01342	A0A0D1XY27	A0A0D2BAX2	Peptidase S53 domain-containing protein.	Allophanate hydrolase.	0.470
PV09_01652	PV09_02086	A0A0D1XY27	A0A0D2B7J9	Peptidase S53 domain-containing protein.	Uncharacterized protein.	0.569
PV09_01652	PV09_02189	A0A0D1XY27	A0A0D2ALE7	Peptidase S53 domain-containing protein.	Uncharacterized protein.	0.489
PV09_01652	PV09_03514	A0A0D1XY27	A0A0D1XSC0	Peptidase S53 domain-containing protein.	SH3 domain-containing protein.	0.480
PV09_01652	PV09_03921	A0A0D1XY27	A0A0D2AEI7	Peptidase S53 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.490
PV09_01652	PV09_05611	A0A0D1XY27	A0A0D1XLW6	Peptidase S53 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.485
PV09_01652	PV09_05856	A0A0D1XY27	A0A0D2AUG9	Peptidase S53 domain-containing protein.	Uncharacterized protein.	0.498
PV09_01652	PV09_06563	A0A0D1XY27	A0A0D2A5S2	Peptidase S53 domain-containing protein.	Polyubiquitin.	0.474
PV09_01652	PV09_08988	A0A0D1XY27	A0A0D2AK35	Peptidase S53 domain-containing protein.	Urea carboxylase.	0.470
PV09_02086	PV09_00248	A0A0D2B7J9	A0A0D1Z8K3	Uncharacterized protein.	26S proteasome regulatory subunit rpn11.	0.496
PV09_02086	PV09_01652	A0A0D2B7J9	A0A0D1XY27	Uncharacterized protein.	Peptidase S53 domain-containing protein.	0.569
PV09_02086	PV09_03514	A0A0D2B7J9	A0A0D1XSC0	Uncharacterized protein.	SH3 domain-containing protein.	0.752

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Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.917

expected number of edges:

14

PPI enrichment p-value:

2.83e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006631

Fatty acid metabolic process

4 of 24

1.61

1.17

0.0030

GO:0019605

Butyrate metabolic process

2 of 2

2.39

0.84

0.0286

GO:0017000

Antibiotic biosynthetic process

3 of 17

1.64

0.77

0.0286

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031177

Phosphopantetheine binding

3 of 3

2.39

1.74

0.00056

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1312

Mixed, incl. AMP-binding enzyme, and Butyrate metabolic process

7 of 10

2.24

5.06

1.07e-11

CL:1286

Mixed, incl. Fatty acid metabolism, and KR domain

8 of 23

1.93

4.31

1.07e-11

CL:1314

AMP-binding enzyme, and Polyketide synthase, ketoreductase domain

3 of 5

2.17

1.84

0.00028

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005777

Peroxisome

4 of 6

2.21

2.6

7.15e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

2 of 4

2.09

0.74

0.0420

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00550

Phosphopantetheine attachment site

5 of 8

2.19

3.27

2.05e-07

PF16197

Ketoacyl-synthetase C-terminal extension

3 of 3

2.39

1.96

0.00021

PF02801

Beta-ketoacyl synthase, C-terminal domain

3 of 4

2.27

1.9

0.00024

PF00109

Beta-ketoacyl synthase, N-terminal domain

3 of 4

2.27

1.9

0.00024

PF00501

AMP-binding enzyme

2 of 4

2.09

0.92

0.0190

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036736

ACP-like superfamily

5 of 8

2.19

3.09

5.38e-07

IPR009081

Phosphopantetheine binding ACP domain

5 of 8

2.19

3.09

5.38e-07

IPR032821

Polyketide synthase, C-terminal extension

3 of 3

2.39

1.83

0.00037

IPR020841

Polyketide synthase, beta-ketoacyl synthase domain

3 of 4

2.27

1.75

0.00048

IPR018201

Beta-ketoacyl synthase, active site

3 of 4

2.27

1.75

0.00048

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

2 of 2

2.39

1.09

0.0097

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