PV09_02426 protein (Verruconis gallopava) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

PV09_02426

Uncharacterized protein. (85 aa)

Predicted Functional Partners:

PV09_00248

0.994

PV09_05628

0.992

PV09_04480

0.990

PV09_01593

0.985

PV09_08748

0.981

PV09_05623

0.976

PV09_01873

0.975

PV09_09584

0.973

PV09_01530

0.970

PV09_05991

0.969

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00248	PV09_01530	A0A0D1Z8K3	A0A0D2AM89	26S proteasome regulatory subunit rpn11.	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	0.999
PV09_00248	PV09_01593	A0A0D1Z8K3	A0A0D1XXX7	26S proteasome regulatory subunit rpn11.	VWFA domain-containing protein.	0.999
PV09_00248	PV09_01873	A0A0D1Z8K3	A0A0D2B9S5	26S proteasome regulatory subunit rpn11.	PCI domain-containing protein.	0.999
PV09_00248	PV09_02426	A0A0D1Z8K3	A0A0D1Z1A0	26S proteasome regulatory subunit rpn11.	Uncharacterized protein.	0.994
PV09_00248	PV09_04480	A0A0D1Z8K3	A0A0D2AYC5	26S proteasome regulatory subunit rpn11.	PCI domain-containing protein.	0.999
PV09_00248	PV09_05623	A0A0D1Z8K3	A0A0D2A8S5	26S proteasome regulatory subunit rpn11.	PCI domain-containing protein.	0.999
PV09_00248	PV09_05628	A0A0D1Z8K3	A0A0D2A8T2	26S proteasome regulatory subunit rpn11.	PCI domain-containing protein.	0.956
PV09_00248	PV09_05991	A0A0D1Z8K3	A0A0D1XKU1	26S proteasome regulatory subunit rpn11.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PV09_00248	PV09_08748	A0A0D1Z8K3	A0A0D1XBK3	26S proteasome regulatory subunit rpn11.	26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999
PV09_00248	PV09_09584	A0A0D1Z8K3	A0A0D1ZX63	26S proteasome regulatory subunit rpn11.	26S proteasome regulatory subunit rpn-8.	0.999
PV09_01530	PV09_00248	A0A0D2AM89	A0A0D1Z8K3	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S proteasome regulatory subunit rpn11.	0.999
PV09_01530	PV09_01593	A0A0D2AM89	A0A0D1XXX7	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	VWFA domain-containing protein.	0.999
PV09_01530	PV09_01873	A0A0D2AM89	A0A0D2B9S5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
PV09_01530	PV09_02426	A0A0D2AM89	A0A0D1Z1A0	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.970
PV09_01530	PV09_04480	A0A0D2AM89	A0A0D2AYC5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
PV09_01530	PV09_05623	A0A0D2AM89	A0A0D2A8S5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.998
PV09_01530	PV09_05628	A0A0D2AM89	A0A0D2A8T2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.904
PV09_01530	PV09_05991	A0A0D2AM89	A0A0D1XKU1	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
PV09_01530	PV09_08748	A0A0D2AM89	A0A0D1XBK3	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999
PV09_01530	PV09_09584	A0A0D2AM89	A0A0D1ZX63	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S proteasome regulatory subunit rpn-8.	0.999

page 1 of 6

Network Stats

number of nodes:

8

number of edges:

14

average node degree:

3.5

avg. local clustering coefficient:

0.917

expected number of edges:

13

PPI enrichment p-value:

0.462

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8254

Mixed, incl. Phosphopantetheine, and Wax biosynthesis

4 of 22

2.69

3.79

3.64e-07

CL:8266

Wax biosynthesis, and Polyketide synthase, ketoreductase domain

3 of 6

3.13

3.52

1.65e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-163765

ChREBP activates metabolic gene expression

3 of 18

2.65

2.53

5.88e-05

MAP-199220

Vitamin B5 (pantothenate) metabolism

3 of 22

2.56

2.51

5.88e-05

MAP-75105

Fatty acyl-CoA biosynthesis

3 of 40

2.3

2.16

0.00018

MAP-163685

Integration of energy metabolism

3 of 60

2.13

1.89

0.00044

MAP-8978868

Fatty acid metabolism

3 of 162

1.69

1.16

0.0063

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

4 of 12

2.95

5.03

3.85e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00550

Phosphopantetheine attachment site

4 of 12

2.95

4.6

2.10e-08

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036736

ACP-like superfamily

4 of 12

2.95

4.34

6.02e-08

IPR009081

Phosphopantetheine binding ACP domain

4 of 12

2.95

4.34

6.02e-08

IPR013968

Polyketide synthase, ketoreductase domain

3 of 8

3.0

3.1

7.79e-06

IPR006162

Phosphopantetheine attachment site

2 of 6

2.95

1.51

0.0035

IPR036291

NAD(P)-binding domain superfamily

3 of 210

1.58

0.74

0.0434

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

2 of 7

2.88

1.59

0.0025

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