PV09_05851 protein (Verruconis gallopava) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PV09_05851

Uncharacterized protein. (126 aa)

Predicted Functional Partners:

PV09_01868

0.647

PV09_05673

0.590

PV09_08596

0.587

PV09_07661

0.587

PV09_00220

0.587

PV09_05100

0.587

PV09_00713

0.555

PV09_06302

0.555

PV09_02221

0.555

PV09_00410

0.545

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00220	PV09_05673	A0A0D2ARZ2	A0A0D2A907	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	NodB homology domain-containing protein.	0.734
PV09_00220	PV09_05851	A0A0D2ARZ2	A0A0D2A872	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Uncharacterized protein.	0.587
PV09_00410	PV09_05100	A0A0D1Z9A3	A0A0D2AX77	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Cell division control protein 48.	0.984
PV09_00410	PV09_05851	A0A0D1Z9A3	A0A0D2A872	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.545
PV09_00410	PV09_07661	A0A0D1Z9A3	A0A0D2A2D2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	AAA domain-containing protein.	0.889
PV09_00410	PV09_08596	A0A0D1Z9A3	A0A0D1XC20	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.974
PV09_00713	PV09_05851	A0A0D1Y116	A0A0D2A872	ABC transporter domain-containing protein.	Uncharacterized protein.	0.555
PV09_01868	PV09_05100	A0A0D2B9R9	A0A0D2AX77	Ubiquitin carboxyl-terminal hydrolase.	Cell division control protein 48.	0.589
PV09_01868	PV09_05851	A0A0D2B9R9	A0A0D2A872	Ubiquitin carboxyl-terminal hydrolase.	Uncharacterized protein.	0.647
PV09_01868	PV09_07661	A0A0D2B9R9	A0A0D2A2D2	Ubiquitin carboxyl-terminal hydrolase.	AAA domain-containing protein.	0.422
PV09_01868	PV09_08596	A0A0D2B9R9	A0A0D1XC20	Ubiquitin carboxyl-terminal hydrolase.	Uncharacterized protein.	0.501
PV09_02221	PV09_05851	A0A0D1Z350	A0A0D2A872	Uncharacterized protein.	Uncharacterized protein.	0.555
PV09_05100	PV09_00410	A0A0D2AX77	A0A0D1Z9A3	Cell division control protein 48.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.984
PV09_05100	PV09_01868	A0A0D2AX77	A0A0D2B9R9	Cell division control protein 48.	Ubiquitin carboxyl-terminal hydrolase.	0.589
PV09_05100	PV09_05851	A0A0D2AX77	A0A0D2A872	Cell division control protein 48.	Uncharacterized protein.	0.587
PV09_05673	PV09_00220	A0A0D2A907	A0A0D2ARZ2	NodB homology domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.734
PV09_05673	PV09_05851	A0A0D2A907	A0A0D2A872	NodB homology domain-containing protein.	Uncharacterized protein.	0.590
PV09_05851	PV09_00220	A0A0D2A872	A0A0D2ARZ2	Uncharacterized protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.587
PV09_05851	PV09_00410	A0A0D2A872	A0A0D1Z9A3	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.545
PV09_05851	PV09_00713	A0A0D2A872	A0A0D1Y116	Uncharacterized protein.	ABC transporter domain-containing protein.	0.555

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.87

expected number of edges:

11

PPI enrichment p-value:

4.02e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019646

Aerobic electron transport chain

4 of 5

2.55

2.99

2.36e-06

GO:0022900

Electron transport chain

6 of 73

1.56

2.07

2.86e-06

GO:0009060

Aerobic respiration

5 of 48

1.67

1.98

1.84e-05

GO:0006091

Generation of precursor metabolites and energy

7 of 131

1.38

1.76

2.48e-06

GO:0034775

Glutathione transmembrane transport

2 of 2

2.65

1.3

0.0042

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

4 of 36

1.69

1.47

0.00063

GO:0015399

Primary active transmembrane transporter activity

5 of 86

1.41

1.27

0.00063

GO:0009055

Electron transfer activity

3 of 45

1.47

0.82

0.0174

GO:0016491

Oxidoreductase activity

7 of 547

0.76

0.53

0.0075

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070069

Cytochrome complex

4 of 4

2.65

3.65

1.34e-07

GO:0005887

Integral component of plasma membrane

3 of 49

1.43

1.06

0.0035

GO:0016021

Integral component of membrane

10 of 869

0.71

0.65

2.13e-05

GO:0005886

Plasma membrane

10 of 1250

0.55

0.46

0.00036

GO:0016020

Membrane

11 of 1776

0.44

0.38

0.00042

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2096

Mixed, incl. Cytochrome complex, and Tripeptide transport

8 of 12

2.47

7.0

2.76e-15

CL:2099

Cytochrome complex, and ABC transporter transmembrane region

7 of 7

2.65

6.86

3.07e-14

CL:1952

Mixed, incl. Oxidative phosphorylation, and Ubiquinone

10 of 84

1.72

4.12

2.46e-14

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

tcu00190

Oxidative phosphorylation

7 of 59

1.72

3.14

2.24e-09

tcu02020

Two-component system

4 of 60

1.47

1.35

0.00050

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070069

Cytochrome complex

4 of 4

2.65

3.47

3.00e-07

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

3 of 45

1.47

0.78

0.0216

GOCC:0005887

Integral component of plasma membrane

3 of 62

1.33

0.74

0.0216

GOCC:0032991

Protein-containing complex

7 of 655

0.68

0.43

0.0216

GOCC:0016020

Membrane

7 of 732

0.63

0.41

0.0216

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1133

Transmembrane helix

10 of 890

0.7

0.62

7.95e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00664

ABC transporter transmembrane region

3 of 10

2.13

1.47

0.0015

PF02322

Cytochrome bd terminal oxidase subunit II

2 of 2

2.65

1.13

0.0088

PF01654

Cytochrome bd terminal oxidase subunit I

2 of 2

2.65

1.13

0.0088

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039421

Type 1 protein exporter

4 of 13

2.14

2.16

5.41e-05

IPR036640

ABC transporter type 1, transmembrane domain superfamily

4 of 13

2.14

2.16

5.41e-05

IPR011527

ABC transporter type 1, transmembrane domain

4 of 13

2.14

2.16

5.41e-05

IPR014223

ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC

2 of 2

2.65

1.12

0.0092

IPR003317

Cytochrome ubiquinol oxidase subunit 2

2 of 2

2.65

1.12

0.0092

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

4 of 135

1.12

0.64

0.0245

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (28%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About