PV09_02413 protein (Verruconis gallopava) - STRING interaction network

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

PV09_02413

Uncharacterized protein. (277 aa)

Predicted Functional Partners:

PV09_00987

0.906

PV09_08007

0.783

PV09_05528

0.712

PV09_01671

0.694

PV09_07308

0.587

PV09_09180

0.587

PV09_00814

0.555

PV09_03576

0.500

PV09_07167

0.460

PV09_07388

0.450

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00814	PV09_02413	A0A0D1Z7F0	A0A0D2AIJ9	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Uncharacterized protein.	0.555
PV09_00814	PV09_07308	A0A0D1Z7F0	A0A0D2A475	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Uncharacterized protein.	0.742
PV09_00814	PV09_07388	A0A0D1Z7F0	A0A0D1XFY4	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family.	0.437
PV09_00814	PV09_09180	A0A0D1Z7F0	A0A0D2AJH5	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Uncharacterized protein.	0.605
PV09_00987	PV09_01671	A0A0D2AMX4	A0A0D1XY48	Uncharacterized protein.	Uncharacterized protein.	0.618
PV09_00987	PV09_02413	A0A0D2AMX4	A0A0D2AIJ9	Uncharacterized protein.	Uncharacterized protein.	0.906
PV09_00987	PV09_03576	A0A0D2AMX4	A0A0D1XSI2	Uncharacterized protein.	Uncharacterized protein.	0.485
PV09_01671	PV09_00987	A0A0D1XY48	A0A0D2AMX4	Uncharacterized protein.	Uncharacterized protein.	0.618
PV09_01671	PV09_02413	A0A0D1XY48	A0A0D2AIJ9	Uncharacterized protein.	Uncharacterized protein.	0.694
PV09_01671	PV09_03576	A0A0D1XY48	A0A0D1XSI2	Uncharacterized protein.	Uncharacterized protein.	0.703
PV09_01671	PV09_07167	A0A0D1XY48	A0A0D1YKM1	Uncharacterized protein.	Uncharacterized protein.	0.505
PV09_01671	PV09_07308	A0A0D1XY48	A0A0D2A475	Uncharacterized protein.	Uncharacterized protein.	0.766
PV09_01671	PV09_09180	A0A0D1XY48	A0A0D2AJH5	Uncharacterized protein.	Uncharacterized protein.	0.909
PV09_02413	PV09_00814	A0A0D2AIJ9	A0A0D1Z7F0	Uncharacterized protein.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.555
PV09_02413	PV09_00987	A0A0D2AIJ9	A0A0D2AMX4	Uncharacterized protein.	Uncharacterized protein.	0.906
PV09_02413	PV09_01671	A0A0D2AIJ9	A0A0D1XY48	Uncharacterized protein.	Uncharacterized protein.	0.694
PV09_02413	PV09_03576	A0A0D2AIJ9	A0A0D1XSI2	Uncharacterized protein.	Uncharacterized protein.	0.500
PV09_02413	PV09_05528	A0A0D2AIJ9	A0A0D1YRR7	Uncharacterized protein.	Uncharacterized protein; Belongs to the FMO family.	0.712
PV09_02413	PV09_07167	A0A0D2AIJ9	A0A0D1YKM1	Uncharacterized protein.	Uncharacterized protein.	0.460
PV09_02413	PV09_07308	A0A0D2AIJ9	A0A0D2A475	Uncharacterized protein.	Uncharacterized protein.	0.587

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

35

PPI enrichment p-value:

0.000516

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000160

Phosphorelay signal transduction system

7 of 79

1.38

1.73

4.26e-06

GO:0018106

Peptidyl-histidine phosphorylation

4 of 36

1.48

1.28

0.00086

GO:0016310

Phosphorylation

5 of 91

1.17

1.01

0.0010

GO:0050896

Response to stimulus

8 of 262

0.92

0.87

7.87e-05

GO:0050794

Regulation of cellular process

9 of 337

0.86

0.83

2.78e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000155

Phosphorelay sensor kinase activity

6 of 40

1.61

2.16

2.46e-06

GO:0016301

Kinase activity

7 of 93

1.31

1.65

2.46e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

9 of 521

0.67

0.55

0.00074

GO:0016021

Integral component of membrane

8 of 568

0.58

0.42

0.0067

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3372

Mixed, incl. MacB, ATP-binding domain, and DegT/DnrJ/EryC1/StrS aminotransferase family

4 of 5

2.34

2.96

1.68e-06

CL:3180

GGDEF domain, and His Kinase A (phosphoacceptor) domain

7 of 44

1.63

2.6

5.83e-08

CL:3234

Two-component regulatory system, and PAS domain

4 of 14

1.89

2.14

2.69e-05

CL:3237

Two-component regulatory system, and cheY-homologous receiver domain

3 of 6

2.13

1.91

0.00019

CL:3191

HPT domain superfamily, and GAF domain

3 of 7

2.06

1.82

0.00025

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

5 of 49

1.44

1.56

6.63e-05

KW-0418

Kinase

6 of 73

1.35

1.54

2.29e-05

KW-0902

Two-component regulatory system

3 of 20

1.61

1.12

0.0041

KW-0067

ATP-binding

6 of 237

0.84

0.62

0.0043

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

7 of 19

2.0

3.94

6.28e-10

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

7 of 22

1.94

3.78

7.42e-10

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

7 of 24

1.9

3.68

8.32e-10

IPR005467

Histidine kinase domain

7 of 25

1.88

3.64

8.32e-10

IPR003594

Histidine kinase/HSP90-like ATPase

7 of 29

1.82

3.41

1.57e-09

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

7 of 21

1.96

4.09

1.06e-10

SM00387

Histidine kinase-like ATPases

7 of 34

1.75

3.29

9.88e-10

SM00448

cheY-homologous receiver domain

5 of 42

1.51

1.82

1.30e-05

SM00073

Histidine Phosphotransfer domain

2 of 4

2.13

1.2

0.0054

SM00304

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain

2 of 10

1.73

0.87

0.0186

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