node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | PV09_00459 | A0A0D2B2P8 | A0A0D2ASB6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ERCC4 domain-containing protein. | 0.905 |
FEN1 | PV09_01637 | A0A0D2B2P8 | A0A0D1XY11 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ENDO3c domain-containing protein. | 0.644 |
FEN1 | PV09_01639 | A0A0D2B2P8 | A0A0D2ALQ5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Vezatin domain-containing protein. | 0.991 |
FEN1 | PV09_01800 | A0A0D2B2P8 | A0A0D2AMB0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.872 |
FEN1 | PV09_02467 | A0A0D2B2P8 | A0A0D2AIQ4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.979 |
FEN1 | PV09_03661 | A0A0D2B2P8 | A0A0D2B1A8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ENDO3c domain-containing protein. | 0.447 |
FEN1 | PV09_05649 | A0A0D2B2P8 | A0A0D2A8W1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AP_endonuc_2 domain-containing protein. | 0.625 |
FEN1 | PV09_07490 | A0A0D2B2P8 | A0A0D2A2J3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.991 |
PV09_00459 | FEN1 | A0A0D2ASB6 | A0A0D2B2P8 | ERCC4 domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.905 |
PV09_00459 | PV09_01637 | A0A0D2ASB6 | A0A0D1XY11 | ERCC4 domain-containing protein. | ENDO3c domain-containing protein. | 0.488 |
PV09_00459 | PV09_01639 | A0A0D2ASB6 | A0A0D2ALQ5 | ERCC4 domain-containing protein. | Vezatin domain-containing protein. | 0.845 |
PV09_00459 | PV09_01800 | A0A0D2ASB6 | A0A0D2AMB0 | ERCC4 domain-containing protein. | Uncharacterized protein. | 0.765 |
PV09_00459 | PV09_03661 | A0A0D2ASB6 | A0A0D2B1A8 | ERCC4 domain-containing protein. | ENDO3c domain-containing protein. | 0.456 |
PV09_00459 | PV09_05649 | A0A0D2ASB6 | A0A0D2A8W1 | ERCC4 domain-containing protein. | AP_endonuc_2 domain-containing protein. | 0.834 |
PV09_00459 | PV09_07490 | A0A0D2ASB6 | A0A0D2A2J3 | ERCC4 domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.845 |
PV09_01637 | FEN1 | A0A0D1XY11 | A0A0D2B2P8 | ENDO3c domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.644 |
PV09_01637 | PV09_00459 | A0A0D1XY11 | A0A0D2ASB6 | ENDO3c domain-containing protein. | ERCC4 domain-containing protein. | 0.488 |
PV09_01637 | PV09_01800 | A0A0D1XY11 | A0A0D2AMB0 | ENDO3c domain-containing protein. | Uncharacterized protein. | 0.842 |
PV09_01637 | PV09_02467 | A0A0D1XY11 | A0A0D2AIQ4 | ENDO3c domain-containing protein. | DNA ligase. | 0.449 |
PV09_01637 | PV09_05382 | A0A0D1XY11 | A0A0D2AAM4 | ENDO3c domain-containing protein. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.489 |