PV09_07851 protein (Verruconis gallopava) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PV09_07851

HET domain-containing protein. (618 aa)

Predicted Functional Partners:

PV09_00068

0.494

PV09_02424

0.478

PV09_09346

0.475

PV09_06010

0.468

PV09_03766

0.465

PV09_04103

0.461

PV09_01029

0.457

PV09_08327

0.452

PV09_05219

0.446

PV09_00087

0.429

Your Current Organism:

Verruconis gallopava

NCBI taxonomy Id: 253628
Other names: ATCC 16027, CBS 437.64, CDC 45-492-62, Dactylaria gallopava, MUCL 6683, Ochroconis gallopava, Scolecobasidium gallopavum, V. gallopava, Verruconis gallopava (W.B. Cooke) Samerpitak & de Hoog, 2014

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV09_00068	PV09_07851	A0A0D1Y253	A0A0D2ANF4	Uncharacterized protein; Belongs to the peptidase M24B family.	HET domain-containing protein.	0.494
PV09_00087	PV09_02424	A0A0D1Y274	A0A0D2AJG5	HET domain-containing protein.	HET domain-containing protein.	0.426
PV09_00087	PV09_03766	A0A0D1Y274	A0A0D2AE17	HET domain-containing protein.	HET domain-containing protein.	0.417
PV09_00087	PV09_06010	A0A0D1Y274	A0A0D2A7N9	HET domain-containing protein.	HET domain-containing protein.	0.424
PV09_00087	PV09_07851	A0A0D1Y274	A0A0D2ANF4	HET domain-containing protein.	HET domain-containing protein.	0.429
PV09_00087	PV09_09346	A0A0D1Y274	A0A0D1X9N8	HET domain-containing protein.	HET domain-containing protein.	0.427
PV09_01029	PV09_02424	A0A0D1XZ66	A0A0D2AJG5	HET domain-containing protein.	HET domain-containing protein.	0.516
PV09_01029	PV09_03766	A0A0D1XZ66	A0A0D2AE17	HET domain-containing protein.	HET domain-containing protein.	0.507
PV09_01029	PV09_06010	A0A0D1XZ66	A0A0D2A7N9	HET domain-containing protein.	HET domain-containing protein.	0.507
PV09_01029	PV09_07851	A0A0D1XZ66	A0A0D2ANF4	HET domain-containing protein.	HET domain-containing protein.	0.457
PV09_01029	PV09_09346	A0A0D1XZ66	A0A0D1X9N8	HET domain-containing protein.	HET domain-containing protein.	0.530
PV09_02424	PV09_00087	A0A0D2AJG5	A0A0D1Y274	HET domain-containing protein.	HET domain-containing protein.	0.426
PV09_02424	PV09_01029	A0A0D2AJG5	A0A0D1XZ66	HET domain-containing protein.	HET domain-containing protein.	0.516
PV09_02424	PV09_04103	A0A0D2AJG5	A0A0D2ADB4	HET domain-containing protein.	HET domain-containing protein.	0.498
PV09_02424	PV09_05219	A0A0D2AJG5	A0A0D2AWC0	HET domain-containing protein.	HET domain-containing protein.	0.460
PV09_02424	PV09_07851	A0A0D2AJG5	A0A0D2ANF4	HET domain-containing protein.	HET domain-containing protein.	0.478
PV09_02424	PV09_08327	A0A0D2AJG5	A0A0D1XD43	HET domain-containing protein.	HET domain-containing protein.	0.567
PV09_03766	PV09_00087	A0A0D2AE17	A0A0D1Y274	HET domain-containing protein.	HET domain-containing protein.	0.417
PV09_03766	PV09_01029	A0A0D2AE17	A0A0D1XZ66	HET domain-containing protein.	HET domain-containing protein.	0.507
PV09_03766	PV09_04103	A0A0D2AE17	A0A0D2ADB4	HET domain-containing protein.	HET domain-containing protein.	0.492

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.715

expected number of edges:

25

PPI enrichment p-value:

0.141

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0097352

Autophagosome maturation

4 of 4

3.23

4.22

2.11e-08

GO:0051228

Mitotic spindle disassembly

4 of 6

3.05

4.1

3.16e-08

GO:0071712

ER-associated misfolded protein catabolic process

4 of 12

2.75

3.68

1.37e-07

GO:0030970

Retrograde protein transport, ER to cytosol

4 of 12

2.75

3.68

1.37e-07

GO:0032984

Protein-containing complex disassembly

5 of 56

2.18

3.33

1.37e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031593

Polyubiquitin modification-dependent protein binding

4 of 22

2.49

3.12

1.16e-06

GO:0016887

ATP hydrolysis activity

7 of 335

1.55

2.22

4.87e-07

GO:0005524

ATP binding

7 of 1292

0.96

0.84

0.00054

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034098

VCP-NPL4-UFD1 AAA ATPase complex

4 of 8

2.93

4.06

3.32e-08

GO:0000328

Fungal-type vacuole lumen

2 of 8

2.63

1.27

0.0048

GO:0000324

Fungal-type vacuole

3 of 176

1.46

0.74

0.0278

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3077

Ubiquitin-dependent ERAD pathway, and Hedgehog ligand biogenesis

6 of 71

2.15

3.86

5.92e-09

CL:3081

UBX domain, and VCP-NPL4-UFD1 AAA ATPase complex

4 of 18

2.57

3.39

3.80e-07

CL:3173

Derlin, and Hedgehog ligand biogenesis

2 of 12

2.45

1.09

0.0101

CL:20347

Mitochondrial calcium ion transport, and Lon protease

2 of 29

2.07

0.76

0.0386

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04141

Protein processing in endoplasmic reticulum

4 of 334

1.31

0.94

0.0050

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5689896

Ovarian tumor domain proteases

6 of 27

2.57

5.63

8.84e-12

MAP-9755511

KEAP1-NFE2L2 pathway

6 of 33

2.49

5.44

1.30e-11

MAP-9711123

Cellular response to chemical stress

6 of 130

1.89

3.24

2.04e-08

MAP-8951664

Neddylation

6 of 149

1.83

3.07

3.39e-08

MAP-5688426

Deubiquitination

6 of 212

1.68

2.56

2.13e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990023

Mitotic spindle midzone

4 of 11

2.79

3.73

1.16e-07

GOCC:0000328

Fungal-type vacuole lumen

2 of 13

2.42

1.16

0.0072

GOCC:0000324

Fungal-type vacuole

3 of 165

1.49

0.82

0.0183

GOCC:0030687

Preribosome, large subunit precursor

2 of 47

1.86

0.74

0.0396

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0132

Cell division

2 of 11

2.49

1.18

0.0070

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF09336

Vps4 C terminal oligomerisation domain

2 of 6

2.75

0.96

0.0185

PF00004

ATPase family associated with various cellular activities (AAA)

2 of 5

2.83

0.96

0.0185

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003959

ATPase, AAA-type, core

7 of 83

2.15

4.51

1.18e-10

IPR003960

ATPase, AAA-type, conserved site

5 of 43

2.29

3.41

1.57e-07

IPR003338

CDC48, N-terminal subdomain

3 of 3

3.23

2.9

5.72e-06

IPR004201

CDC48, domain 2

3 of 4

3.1

2.81

8.00e-06

IPR041569

AAA ATPase, AAA+ lid domain

4 of 26

2.42

2.8

4.46e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01073

Cell division protein 48 (CDC48) N-terminal domain

3 of 3

3.23

3.18

1.73e-06

SM00382

ATPases associated with a variety of cellular activities

5 of 170

1.7

2.12

8.66e-06

SM01072

Cell division protein 48 (CDC48) domain 2

2 of 2

3.23

1.91

0.00036

SM00244

Prohibitin homologues

2 of 7

2.68

1.53

0.0016

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (30%) [HD]

Permalink

Network

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About