STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL18572.1Conserved hypothetical protein. (107 aa)    
Predicted Functional Partners:
EFL18573.1
Integral membrane protein.
    
  0.775
EFL14354.1
Nicotinamide-nucleotide adenylyltransferase.
    
 0.616
EFL13569.1
Predicted protein.
       0.557
EFL17339.1
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.548
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.506
EFL14247.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.499
EFL18395.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.499
EFL16910.1
Oxidoreductase.
    
  0.467
EFL20180.1
Oxidoreductase.
    
  0.467
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.464
Your Current Organism:
Streptomyces sp. C
NCBI taxonomy Id: 253839
Other names: S. sp. C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.