STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL19631.1Phosphodiesterase. (168 aa)    
Predicted Functional Partners:
EFL13973.1
Ankyrin domain-containing protein.
    
 
 0.915
EFL18985.1
Predicted protein.
    
 
 0.915
EFL19254.1
Ankyrin repeat protein.
    
 
 0.915
EFL15391.1
Ribonuclease PH/Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.888
EFL17325.1
Peroxiredoxin.
   
 
 0.710
EFL19674.1
Predicted protein.
       0.557
EFL19632.1
2-hydroxycyclohexanecarboxyl-CoA dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.468
EFL19776.1
WD-40 repeat-containing protein.
    
 
 0.460
EFL18934.1
Predicted protein.
      
 0.424
EFL12925.1
Predicted protein.
  
     0.420
Your Current Organism:
Streptomyces sp. C
NCBI taxonomy Id: 253839
Other names: S. sp. C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.