node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIQ07104.1 | cobB | SAMN05421682_102239 | SAMN05421682_10975 | Nicotinamidase/pyrazinamidase. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.930 |
cobB | SIQ07104.1 | SAMN05421682_10975 | SAMN05421682_102239 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Nicotinamidase/pyrazinamidase. | 0.930 |
cobB | deoD | SAMN05421682_10975 | SAMN05421682_101438 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Purine-nucleoside phosphorylase. | 0.922 |
cobB | dnaK | SAMN05421682_10975 | SAMN05421682_10613 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.858 |
cobB | draG | SAMN05421682_10975 | SAMN05421682_10976 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | ADP-ribosylglycohydrolase. | 0.782 |
cobB | gdh | SAMN05421682_10975 | SAMN05421682_10876 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.916 |
cobB | kptA | SAMN05421682_10975 | SAMN05421682_10977 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. | 0.772 |
cobB | nadD | SAMN05421682_10975 | SAMN05421682_101208 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.933 |
cobB | nadE | SAMN05421682_10975 | SAMN05421682_10681 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.923 |
cobB | nudC | SAMN05421682_10975 | SAMN05421682_11286 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | NUDIX domain-containing protein. | 0.913 |
cobB | ppnK | SAMN05421682_10975 | SAMN05421682_10824 | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.920 |
deoD | cobB | SAMN05421682_101438 | SAMN05421682_10975 | Purine-nucleoside phosphorylase. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.922 |
deoD | nadD | SAMN05421682_101438 | SAMN05421682_101208 | Purine-nucleoside phosphorylase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.436 |
dnaK | cobB | SAMN05421682_10613 | SAMN05421682_10975 | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.858 |
draG | cobB | SAMN05421682_10976 | SAMN05421682_10975 | ADP-ribosylglycohydrolase. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.782 |
draG | kptA | SAMN05421682_10976 | SAMN05421682_10977 | ADP-ribosylglycohydrolase. | Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. | 0.850 |
gdh | cobB | SAMN05421682_10876 | SAMN05421682_10975 | Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.916 |
kptA | cobB | SAMN05421682_10977 | SAMN05421682_10975 | Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.772 |
kptA | draG | SAMN05421682_10977 | SAMN05421682_10976 | Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. | ADP-ribosylglycohydrolase. | 0.850 |
nadD | cobB | SAMN05421682_101208 | SAMN05421682_10975 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.933 |