STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrH-2UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.954
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
 0.936
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.929
udk
Uridine kinase.
   
 
 0.926
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.925
pyrR
Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.915
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 
0.907
ANX13941.1
Bifunctional metallophosphatase/5'-nucleotidase; Belongs to the 5'-nucleotidase family.
   
 
  0.902
ANX11353.1
Hypothetical protein; Belongs to the 5'-nucleotidase family.
   
 
  0.901
ANX13788.1
Hypothetical protein; Belongs to the 5'-nucleotidase family.
   
 
  0.901
Your Current Organism:
Fictibacillus arsenicus
NCBI taxonomy Id: 255247
Other names: Bacillus arsenicus, Bacillus arsenicus Shivaji et al. 2005, Bacillus sp. JP44SK14, DSM 15822, F. arsenicus, Fictibacillus arsenicus (Shivaji et al. 2005) Glaeser et al. 2013, JCM 12167, MTCC 4380, strain Con a/3
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