STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0006Hypothetical protein; Doubtful CDS. No significant database matches. (145 aa)    
Predicted Functional Partners:
DIP0007
Hypothetical protein; Doubtful CDS. No significant database matches.
       0.616
DIP0008
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 7.1 kDa protein SC10A5.13 TR:O54104 (EMBL:AL021529) (64 aa) fasta scores: E(): 0.18, 52.5% id in 40 aa.
       0.616
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.547
DIP0010
Putative membrane protein; Similar in its C-terminal region to Mycobacterium leprae hypothetical 32.2 kDa protein MLB1770.07 or ML0007 TR:O32870 (EMBL:Z70722) (303 aa) fasta scores: E(): 9.9e-08, 36.28% id in 113 aa.
       0.547
DIP0732
Hypothetical protein; No significant database matches.
  
     0.428
DIP1352
Hypothetical protein; No significant database matches.
  
     0.421
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.