Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DIP0027Putative membrane protein; Similar to Mycobacterium tuberculosis putative transmembrane protein Rv0110 or MTV031.04 TR:O53632 (EMBL:AL021926) (249 aa) fasta scores: E(): 1.4e-13, 34.19% id in 193 aa. (205 aa)    
Predicted Functional Partners:
DIP2375
Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase CwlM or Rv3915 or MTV028.06 TR:O53593 (EMBL:AL021426) (406 aa) fasta scores: E(): 5.4e-78, 52.38% id in 399 aa, and to Bacillus subtilis N-acetylmuramoyl-L-alanine amidase CwlB precursor or LytC SW:CWLB_BACSU (Q02114) (496 aa) fasta scores: E(): 2.8e-07, 25.62% id in 199 aa.
   
   0.695
DIP0026
Putative transposase (partial); Similar to Streptococcus mutans transposase (fragment) TR:Q9ZHF4 (EMBL:AF065413) (75 aa) fasta scores: E(): 3.5e-11, 47.22% id in 72 aa.
       0.535
tatB
Putative Sec-independent twin-arginine translocase system protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
   
 
 0.422
tatA
Sec-independent twin-arginine translocase system protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.422
DIP0861
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 21.3 kDa protein ML0181 or MLCB373.33c TR:Q9Z5G2 (EMBL:AL035500) (197 aa) fasta scores: E(): 2.1e-14, 34.73% id in 190 aa; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 0.410
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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