STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0034Similar to Escherichia coli adenylyltransferase ThiF or B3992 SW:THIF_ECOLI (P30138) (251 aa) fasta scores: E(): 1.1e-21, 35.86% id in 237 aa. (337 aa)    
Predicted Functional Partners:
DIP1072
Putative aminotransferase, class V; Similar to Mycobacterium tuberculosis CDC1551 aminotransferase, class V MT3109 TR:AAK47439 (EMBL:AE007129) (393 aa) fasta scores: E(): 1.1e-52, 45.71% id in 385 aa, and to Mycobacterium tuberculosis NifS-like protein Rv3025c or MTV012.40C TR:O53272 (EMBL:AL021287) (393 aa) fasta scores: E(): 1.1e-52, 45.71% id in 385 aa, and to Ruminococcus flavefaciens cysteine desulfurase IscS or NifS SW:ISCS_RUMFL (O54055) (396 aa) fasta scores: E(): 2.1e-40, 36.48% id in 381 aa.
 
 
 0.986
thiG
Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.980
DIP0493
Putative bifunctional molybdopterim biosynthesis protein; N-terminal region similar to the C-terminal region of Synechococcus sp molybdenum cofactor biosynthesis protein CB MoaCB SW:MOCB_SYNP7 (Q56208) (319 aa) fasta scores: E(): 5.2e-09, 35.06% id in 154 aa and C-terminal region similar to Mycobacterium tuberculosis molybdopterin converting factor subunit 2 MoAE or Rv3119 or MT3201 or MTCY164.29 SWALL:MOAE_MYCTU (SWALL:O05795) (147 aa) fasta scores: E(): 5.7e-11, 38.97% id in 136 aa.
 
 0.966
DIP0032
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 6.6 kDa protein SC6E10.02 TR:Q9S2N5 (EMBL:AL109661) (66 aa) fasta scores: E(): 1.1e-06, 36.36% id in 66 aa.
  
 
 0.963
DIP0492
Putative molybdopterin biosynthesis protein; Similar to Synechococcus sp MTP-synthase sulfurylase MoeB TR:O54307 (EMBL:Y16560) (391 aa) fasta scores: E(): 1.1e-37, 39.56% id in 369 aa.
 
  
0.940
thiD
Similar to Escherichia coli phosphomethylpyrimidine kinase ThiD or B2103 SW:THID_ECOLI (P76422) (266 aa) fasta scores: E(): 5.5e-30, 44.9% id in 265 aa.
 
  
 0.926
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.925
thiE
Putative thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.920
pheT
Similar to Mycobacterium tuberculosis phenylalanyl-tRNA synthetase beta chain PheT or Rv1650 or MT1688 or MTCY06H11.15 SWALL:SYFB_MYCTU (SWALL:P94985) (831 aa) fasta scores: E(): 4.2e-156, 49.64% id in 844 aa, and to Bacillus subtilis phenylalanyl-tRNA synthetase beta chain PheT SWALL:SYFB_BACSU (SWALL:P17922) (804 aa) fasta scores: E(): 1.8e-53, 30.69% id in 847 aa.
  
 
 0.896
thiO
Similar to Rhizobium etli putative thiamine biosynthesis oxidoreductase ThiO SW:THIO_RHIET (O34292) (327 aa) fasta scores: E(): 5.4e-09, 31.67% id in 341 aa.
 
  
 0.881
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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