STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pknBSimilar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa. (673 aa)    
Predicted Functional Partners:
odhI
Putative signal transduction protein; An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase (By similarity).
 
 
 
 0.999
DIP0057
Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa.
 
 0.998
DIP0058
Putative secreted protein; Similar to Mycobacterium leprae hypothetical 17.2 kDa protein MLB1770.14c or ML0021 TR:Q50189 (EMBL:Z70722) (155 aa) fasta scores: E(): 2.3e-13, 35% id in 160 aa.
 
 
 
 0.997
DIP0059
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 30.8 kDa protein SCH69.13 TR:Q9XA21 (EMBL:AL079308) (290 aa) fasta scores: E(): 3.1e-11, 27.6% id in 297 aa.
 
 
 
 0.997
pbpA
Similar to Mycobacterium leprae putative penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa.
 
   
 0.979
pknA
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PnkA or ML0017 SW:PKNA_MYCLE (P54743) (437 aa) fasta scores: E(): 4e-37, 41.99% id in 431 aa.
 
 
0.977
ftsW
Similar to Mycobacterium tuberculosis probable cell division protein FtsW or Rv0017c or MT0020 or MTCY10H4.17c SW:FTSW_MYCTU (P71587) (469 aa) fasta scores: E(): 8.7e-72, 48.61% id in 434 aa, and to Escherichia coli rod shape-determining protein MrdB or RodA or B0634 or Z0780 or ECS0672 SW:RODA_ECOLI (P15035) (370 aa) fasta scores: E(): 8.5e-19, 26.57% id in 365 aa; Belongs to the SEDS family.
 
 
 0.964
ag84
Antigen 84; Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three putative colied-coil regions (residues 84..131, 193..235, 248..273).
  
 
 0.922
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.891
DIP1880
Putative exported protein; Poor database matches. Weakly similar to Streptomyces coelicolor hypothetical protein SC4G6.36 TR:Q9S2S3 (EMBL:AL096884) (266 aa) fasta scores: E(): 4.7e-06, 26.22% id in 225 aa, and to Mycobacterium leprae possible conserved membrane protein ML1667 TR:Q9CBS4 (EMBL:AL583923) (264 aa) fasta scores: E(): 1.5e-05, 28.77% id in 212 aa.
      
 0.837
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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