STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsWSimilar to Mycobacterium tuberculosis probable cell division protein FtsW or Rv0017c or MT0020 or MTCY10H4.17c SW:FTSW_MYCTU (P71587) (469 aa) fasta scores: E(): 8.7e-72, 48.61% id in 434 aa, and to Escherichia coli rod shape-determining protein MrdB or RodA or B0634 or Z0780 or ECS0672 SW:RODA_ECOLI (P15035) (370 aa) fasta scores: E(): 8.5e-19, 26.57% id in 365 aa; Belongs to the SEDS family. (449 aa)    
Predicted Functional Partners:
pbpA
Similar to Mycobacterium leprae putative penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa.
 
 0.999
ftsI
Putative penicillin-binding (cell division related) protein; Similar to Corynebacterium glutamicum penicillin-binding protein FtsI TR:Q9FAD4 (EMBL:AB041009) (704 aa) fasta scores: E(): 3.1e-122, 59.38% id in 677 aa, and to Streptomyces coelicolor FtsI TR:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 2e-42, 32.24% id in 611 aa.
 
 0.971
pknB
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa.
 
 
 0.964
pknA
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PnkA or ML0017 SW:PKNA_MYCLE (P54743) (437 aa) fasta scores: E(): 4e-37, 41.99% id in 431 aa.
 
 
 0.950
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
 
 0.940
DIP0058
Putative secreted protein; Similar to Mycobacterium leprae hypothetical 17.2 kDa protein MLB1770.14c or ML0021 TR:Q50189 (EMBL:Z70722) (155 aa) fasta scores: E(): 2.3e-13, 35% id in 160 aa.
 
   
 0.930
murG
UDP-N-acetylglucosamine-N-acetylmuramyl (pentapeptide); Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.924
DIP0057
Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa.
  
  
 0.917
DIP0059
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 30.8 kDa protein SCH69.13 TR:Q9XA21 (EMBL:AL079308) (290 aa) fasta scores: E(): 3.1e-11, 27.6% id in 297 aa.
 
   
 0.908
DIP1596
Putative cell division protein precursor; Essential cell division protein.
  
 
 0.868
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.