STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0057Similar to Mycobacterium leprae probable phosphoprotein phosphatase Ppp TR:Q50188 (EMBL:Z70722) (509 aa) fasta scores: E(): 5.8e-46, 43.64% id in 488 aa. (485 aa)    
Predicted Functional Partners:
pknB
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PknB or ML0016 SW:PKNB_MYCLE (P54744) (622 aa) fasta scores: E(): 5.7e-58, 43.26% id in 661 aa.
 
 0.998
pknA
Similar to Mycobacterium leprae probable serine/threonine-protein kinase PnkA or ML0017 SW:PKNA_MYCLE (P54743) (437 aa) fasta scores: E(): 4e-37, 41.99% id in 431 aa.
 
 
 0.994
DIP1615
Similar to Streptomyces coelicolor eukaryotic-type protein kinase PkaF TR:Q9ZNB3 (EMBL:AB019394) (629 aa) fasta scores: E(): 8.2e-37, 36.22% id in 646 aa.
 
 
 0.985
DIP0058
Putative secreted protein; Similar to Mycobacterium leprae hypothetical 17.2 kDa protein MLB1770.14c or ML0021 TR:Q50189 (EMBL:Z70722) (155 aa) fasta scores: E(): 2.3e-13, 35% id in 160 aa.
 
 
 0.958
DIP0059
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 30.8 kDa protein SCH69.13 TR:Q9XA21 (EMBL:AL079308) (290 aa) fasta scores: E(): 3.1e-11, 27.6% id in 297 aa.
 
 
 0.956
pbpA
Similar to Mycobacterium leprae putative penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa.
  
  
 0.937
ftsW
Similar to Mycobacterium tuberculosis probable cell division protein FtsW or Rv0017c or MT0020 or MTCY10H4.17c SW:FTSW_MYCTU (P71587) (469 aa) fasta scores: E(): 8.7e-72, 48.61% id in 434 aa, and to Escherichia coli rod shape-determining protein MrdB or RodA or B0634 or Z0780 or ECS0672 SW:RODA_ECOLI (P15035) (370 aa) fasta scores: E(): 8.5e-19, 26.57% id in 365 aa; Belongs to the SEDS family.
  
  
 0.917
DIP2053
Putative protein kinase; Similar to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknG or Rv0410c or MT0423 or MTCY22G10.06c SWALL:PKNG_MYCTU (SWALL:P96256) (750 aa) fasta scores: E(): 2.8e-52, 44.97% id in 656 aa, and to Mycobacterium tuberculosis probable serine/threonine-protein kinase PknL or Rv2176 or MT2232 or MTV021.09 SWALL:PKNL_MYCTU (SWALL:O53510) (399 aa) fasta scores: E(): 4e-06, 28.61% id in 318 aa.
 
 
 0.827
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.779
crgA
Putative membrane protein; Involved in cell division; Belongs to the CrgA family.
     
 0.721
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: high (88%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.