STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0064Putative two-component system response regulator; Similar to Enterococcus faecalis VicR protein TR:Q9REA7 (EMBL:AJ012050) (283 aa) fasta scores: E(): 5.5e-35, 44.978% id in 229 aa, to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP SW:PHOP_BACSU (P13792) (240 aa) fasta scores: E(): 3e-34, 42.918% id in 233 aa, and to Bacillus subtilis hypothetical sensory transduction protein YycF SW:YYCF_BACSU (P37478) (235 aa) fasta scores: E(): 1.8e-33, 43.478% id in 230 aa. (240 aa)    
Predicted Functional Partners:
DIP0063
Putative two-component system sensor protein; Similar to Escherichia coli sensor protein BaeS or B2078 SW:BAES_ECOLI (P30847) (467 aa) fasta scores: E(): 1.8e-28, 33.333% id in 372 aa.
   0.982
DIP1935
Putative two somponent system sensor kinase protein; C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv0758 TR:P71815 (EMBL:Z80226) (485 aa) fasta scores: E(): 7.7e-38, 42.88% id in 471 aa, and to Bacillus halodurans two-component sensor histidine kinase BH0373 TR:Q9KFU8 (EMBL:AP001508) (459 aa) fasta scores: E(): 3.7e-29, 30.81% id in 464 aa.
 
 
 0.902
DIP0390
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis sensor-like histidine kinase SenX3 or Rv0490 or MT0509 or MTCY20G9.16 SW:SEX3_MYCTU (Q11155) (410 aa) fasta scores: E(): 3.6e-60, 48.84% id in 389 aa.
 
 0.894
DIP0287
Similar to Escherichia coli sensor protein RcsC or B2218 SW:RCSC_ECOLI (P14376) (933 aa) fasta scores: E(): 5.5e-10, 26.339% id in 224 aa, and to Pseudomonas syringae sensor protein GacS or LemA SW:GACS_PSESY (P48027) (907 aa) fasta scores: E(): 2e-09, 27.530% id in 247 aa.
 
 
 0.860
mtrB
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis MtrB or Rv3245c or MTCY20B11.20c TR:O05890 (EMBL:Z95121) (567 aa) fasta scores: E(): 4.6e-89, 53.73% id in 482 aa, and to Streptomyces coelicolor sensor protein AfsQ2 or 2SCK8.32c SW:AFQ2_STRCO (Q04943) (535 aa) fasta scores: E(): 1.4e-23, 30.64% id in 447 aa.
 
 
 0.859
DIP0855
Putative two component system sensor kinase; Similar to Corynebacterium glutamicum sensor kinase TR:Q9F160 (EMBL:AF119221) (455 aa) fasta scores: E(): 6.5e-71, 46.98% id in 447 aa, and to Burkholderia pseudomallei sensor protein IrlS SW:IRLS_BURPS (O31396) (464 aa) fasta scores: E(): 4.6e-18, 26% id in 446 aa.
 
 
 0.856
DIP0066
Putative exported protein; No database matches.
 
  
 0.829
DIP0061
IS1628 transposase (pseudogene); Anomalous G+C content (63.8%) and dinucleotide signature. Putative metal transport system. Present also in C.glutamicum.
 
   
 0.726
DIP0067
Putative exported multicopper oxidase; Similar to Mycobacterium tuberculosis CDC1551 copper-binding protein, putative MT0869 TR:AAK45112 (EMBL:AE006975) (504 aa) fasta scores: E(): 9e-68, 43.028% id in 502 aa, and to Nicotiana tabacum L-ascorbate oxidase precursor Aao SW:ASO_TOBAC (Q40588) (578 aa) fasta scores: E(): 2.5e-14, 25.344% id in 509 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRQFLL) at the N-terminal region.
 
  
 0.698
DIP0062
Putative heavy metal-associated transport protein; Similar to Deinococcus radiodurans conserved hypothetical protein DR2452 TR:Q9RRN6 (EMBL:AE002074) (68 aa) fasta scores: E(): 0.0038, 43.103% id in 58 aa, and to Streptococcus pyogenes putative copper chaperone-copper transport operon CopZ or SPY1714 TR:Q99YG6 (EMBL:AE006600) (67 aa) fasta scores: E(): 0.0065, 40.000% id in 60 aa, and to Pseudomonas syringae Plasmid pPaCu1 copper resistance operon ORFH protein TR:Q9KWM7 (EMBL:AB033420) (65 aa) fasta scores: E(): 0.025, 40.000% id in 60 aa, and to Candida albicans copper-transporting p- [...]
  
    0.679
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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