STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0091Putative two-component system response regulator; Similar to Streptomyces lividans response regulator homolog TR:P72471 (EMBL:U63847) (225 aa) fasta scores: E(): 2.7e-29, 42.98% id in 221 aa, and to Streptomyces coelicolor putative two-component system regulator SCH10.18c TR:Q9X8Q7 (EMBL:AL049754) (228 aa) fasta scores: E(): 3e-26, 38.53% id in 218 aa. (219 aa)    
Predicted Functional Partners:
DIP0092
Similar to Streptomyces coelicolor putative two component sensor kinase SC5F7.35c TR:Q9S2S0 (EMBL:AL096872) (416 aa) fasta scores: E(): 2.9e-17, 32.79% id in 308 aa, and to Streptomyces coelicolor putative two-component system sensor kinase SCH10.17c TR:Q9X8Q6 (EMBL:AL049754) (472 aa) fasta scores: E(): 1.1e-11, 33.61% id in 241 aa.
 
 
 0.975
cstS
Histidine kinase; Almost identical to already sequenced Corynebacterium diphtheriae histidine kinase CstS TR:Q9RPE8 (EMBL:AF161328) (408 aa) fasta scores: E(): 2e-149, 97.3% id in 408 aa.
 
 0.870
chrS
Two-component system histidine kinase ChrS; Previously sequenced and described as Corynebacterium diphtheriae histidine kinase ChrS SWALL:Q9RPF0 (EMBL:AF161327) (417 aa) fasta scores: E(): 4e-136, 88.72% id in 417 aa. Similar to many eg. Streptomyces reticuli histidine autokinase SenS SWALL:Q9RIM1 (EMBL:Y14336) (398 aa) fasta scores: E(): 1.6e-21, 35.28% id in 411 aa.
 
 
 0.870
DIP2268
Similar to Streptomyces coelicolor putative two component system histidine kinase SC10A9.11 SWALL:Q9AK93 (EMBL:AL583943) (404 aa) fasta scores: E(): 7.7e-36, 37.15% id in 401 aa, and to Corynebacterium diphtheriae histidine kinase ChrS (DIP2326) SWALL:Q9RPF0 (EMBL:AF161327) (417 aa) fasta scores: E(): 8.2e-25, 31.17% id in 401 aa.
 
 0.869
DIP0090
ABC transport system ATP-binding protein; Similar to Lactococcus lactis NisF TR:Q48597 (EMBL:U17255) (225 aa) fasta scores: E(): 1.3e-25, 43.8% id in 226 aa, and to Staphylococcus epidermidis putative ABC transporter subunit EpiF TR:Q54002 (EMBL:U77778) (231 aa) fasta scores: E(): 7.1e-21, 38.15% id in 228 aa.
       0.765
DIP0089
Putative antibiotic production protein (pseudogene); Pseudogene. Similar to Pseudomonas chlororaphis phenazine biosynthesis protein PhzF or PhzC SW:PHZF_PSECL (Q51520) (278 aa) fasta scores: E(): 1.1e-11, 32.92% id in 246 aa, and to Pseudomonas fluorescens phenazine biosynthesis protein PhzF SW:PHZF_PSEFL (Q51792) (278 aa) fasta scores: E(): 1.8e-11, 32.38% id in 247 aa. Presents a frameshift at residue 109.
       0.617
DIP0093
Probable membrane protein. No database matches.
       0.533
DIP0599
Similar to Streptomyces coelicolor putative two-component system sensor kinase SCD63A.02 TR:Q9KY73 (EMBL:AL356832) (430 aa) fasta scores: E(): 3e-12, 37.09% id in 434 aa.
  
 
 0.500
DIP2107
Similar to Streptomyces coelicolor putative integral membrane transport protein SCD10.28c TR:Q9K3U9 (EMBL:AL359988) (550 aa) fasta scores: E(): 6.2e-18, 25.27% id in 542 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
   
 
 0.421
DIP0094
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.411
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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