STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0101Putative membrane protein; Similar to Mycobacterium tuberculosis DipZ protein Rv2874 or MT2942 or MTCY274.05 SW:DIPZ_MYCTU (Q10801) (695 aa) fasta scores: E(): 1.6e-43, 43.65% id in 591 aa. (546 aa)    
Predicted Functional Partners:
DIP0099
Similar to Streptomyces coelicolor putative RNA polymerase sigma factor SCI11.12c TR:Q9S2A7 (EMBL:AL096849) (185 aa) fasta scores: E(): 2.8e-25, 47.36% id in 171 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 3.9e-10, 31.39% id in 172 aa; Belongs to the sigma-70 factor family. ECF subfamily.
 
   
 0.906
DIP0414
Putative cytochrome C related protein; Similar to Mycobacterium tuberculosis CDC1551 cytochrome C assembly family protein MT0551 TR:AAK44774 (EMBL:AE006954) (324 aa) fasta scores: E(): 6.3e-54, 47.81% id in 320 aa.
  
  
 0.870
msrA
Peptide methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.816
dirA
Almost identical to previously sequenced Corynebacterium diphtheriae iron repressible polypeptide DirA TR:Q46025 (EMBL:U18620) (198 aa) fasta scores: E(): 8.8e-79, 98.99% id in 198 aa, and to Mycobacterium smegmatis alkyl hydroperoxide reductase C AhpC TR:Q57529 (EMBL:U43719) (195 aa) fasta scores: E(): 5.2e-52, 66.12% id in 186 aa.
  
 0.814
qcrC
Ubiquinol-cytochrome C reductase cytochrome C subunit; Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
   
 
 0.776
DIP0098
Putative membrane protein; Weakly similar to Mycobacterium tuberculosis hypothetical 23.9 kDa protein Rv0444c or MTV037.08C TR:O53729 (EMBL:AL021932) (232 aa) fasta scores: E(): 0.004, 25.94% id in 212 aa.
     
 0.774
trxB
Thioredoxin reductase; Similar to Mycobacterium smegmatis thioredoxin reductase TrxB SW:TRXB_MYCSM (O30973) (311 aa) fasta scores: E(): 3.1e-72, 64.82% id in 307 aa.
  
 
 0.763
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.737
DIP0413
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 57.1 kDa protein Rv0528 or MTCY25D10.07 TR:O06394 (EMBL:Z95558) (529 aa) fasta scores: E(): 3.9e-103, 49.43% id in 532 aa.
  
  
 0.684
hemL
Similar to Streptomyces coelicolor glutamate-1-semialdehyde 2,1-aminomutase HemL or SCD65.12 SW:GSA_STRCO (Q9F2S0) (438 aa) fasta scores: E(): 4e-96, 62.97% id in 424 aa, and to Escherichia coli glutamate-1-semialdehyde 2,1-aminomutase HemL or Gsa or PopC or B0154 SW:GSA_ECOLI (P23893) (426 aa) fasta scores: E(): 1.7e-75, 52.39% id in 418 aa.
  
  
 0.642
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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