Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP0104Putative peptidase; Similar to Streptomyces coelicolor putative peptidase SCI52.18c TR:Q9AD91 (EMBL:AL590507) (445 aa) fasta scores: E(): 1e-31, 32.04% id in 440 aa. (448 aa)    
Predicted Functional Partners:
DIP0103
Similar to Mycobacterium leprae hypothetical protein ML2114 TR:Q9CBE3 (EMBL:AL583924) (56 aa) fasta scores: E(): 1.7e-05, 52.08% id in 48 aa.
       0.768
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
 0.705
DIP0106
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 8.6 kDa protein Rv1590 or MT1625 or MTCY336.14c TR:O06600 (EMBL:Z95586) (79 aa) fasta scores: E(): 4.1e-11, 67.24% id in 58 aa.
       0.698
DIP0397
Putative secreted protein; Similar to Streptomyces coelicolor putative membrane protein SCBAC16H6.28 TR:CAC44607 (EMBL:AL596162) (270 aa) fasta scores: E(): 4.9e-22, 39.13% id in 207 aa.
      
 0.618
tipA
Similar to Streptomyces coelicolor transcriptional activator TipA or SCE9.20 SW:TIPA_STRCO (P32184) (253 aa) fasta scores: E(): 5.3e-24, 35.85% id in 251 aa.
       0.611
dapE
Similar to Corynebacterium glutamicum succinyl-diaminopimelate desuccinylase DapE SW:DAPE_CORGL (Q59284) (369 aa) fasta scores: E(): 1.2e-87, 61.11% id in 360 aa, and to Escherichia coli succinyl-diaminopimelate desuccinylase DapE or MsgB or B2472 SW:DAPE_ECOLI (P24176) (375 aa) fasta scores: E(): 3.8e-09, 28.53% id in 354 aa.
  
   
 0.578
argF
Ornithine carbamoyltransferase, anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.560
argD
Similar to Corynebacterium glutamicum acetylornithine aminotransferase ArgD SWALL:ARGD_CORGL (SWALL:Q59282) (389 aa) fasta scores: E(): 2.9e-98, 65.21% id in 391 aa, and to Mycobacterium tuberculosis acetylornithine aminotransferase ArgD or Rv1655 or MT1693 or MTCY06H11.20 SWALL:ARGD_MYCTU (SWALL:P94990) (400 aa) fasta scores: E(): 5.2e-74, 50.12% id in 405 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.549
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
  
 0.436
DIP0555
Putative surface-anchored membrane protein; Very low similarity to Mycobacterium tuberculosis hypothetical protein Rv3448 or MTCY77.20 or MT3554 SWALL:O33354 (EMBL:Z95390) (467 aa) fasta scores: E(): 0.0016, 21.96% id in 478 aa. Note: Contains a putative sortase anchor site (LPNTG).
  
     0.428
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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