STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0115Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 39.2 kDa protein SCH24.21c TR:Q9X8T5 (EMBL:AL049826) (360 aa) fasta scores: E(): 5e-111, 79.49% id in 356 aa. (355 aa)    
Predicted Functional Partners:
impA
Similar to Corynebacterium glutamicum inositol monophosphate phosphatase ImpA TR:O52736 (EMBL:AF045998) (259 aa) fasta scores: E(): 3.2e-42, 50.42% id in 236 aa, and to Mycobacterium smegmatis inositol monophosphate phosphatase ImpA TR:O51845 (EMBL:AF005905) (276 aa) fasta scores: E(): 8e-34, 42.35% id in 255 aa.
   
 
 0.973
DIP1403
Putative hydrolase; Similar to Mycobacterium tuberculosis inositol-1-monophosphatase SuhB or Rv2701c or MT2775 or MTCY05A6.22c SW:SUHB_MYCTU (O07203) (290 aa) fasta scores: E(): 1e-38, 45% id in 280 aa, and to Escherichia coli inositol-1-monophosphatase SuhB or SsyA or B2533 SW:SUHB_ECOLI (P22783) (267 aa) fasta scores: E(): 3.2e-19, 37.22% id in 231 aa.
   
 
 0.951
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm SW:PGMU_ECOLI (P36938) (546 aa) fasta scores: E(): 2.7e-133, 62.5% id in 544 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3068c TR:P95090 (EMBL:Z83866) (547 aa) fasta scores: E(): 7e-150, 69.76% id in 549 aa.
     
 0.918
glk
Glucose kinase; Similar to Corynebacterium glutamicum glucose kinase Glk TR:Q9KKE7 (EMBL:AF096280) (323 aa) fasta scores: E(): 2.5e-79, 62.38% id in 319 aa, and to Streptomyces coelicolor glucokinase Glk or SC6E10.20c SW:GLK_STRCO (P40184) (317 aa) fasta scores: E(): 5.7e-45, 40% id in 310 aa.
     
  0.900
DIP1386
Putative phosphatidyltransferase; Similar to Mycobacterium tuberculosis CDC1551 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putative MT2687 SWALL:AAK47003 (EMBL:AE007101) (217 aa) fasta scores: E(): 6.9e-34, 48.29% id in 205 aa, and to Mycobacterium smegmatis phosphatidylinositol synthase PgsA SWALL:Q9F7Y9 (EMBL:AF265558) (222 aa) fasta scores: E(): 8.7e-31, 47% id in 200 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
   
 0.724
DIP1969
Putative LacI-family transcriptional regulator; Similar to Escherichia coli raffinose operon repressor RafR SW:RAFR_ECOLI (P21867) (335 aa) fasta scores: E(): 1.5e-08, 24.52% id in 367 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3575c TR:P96857 (EMBL:Z92774) (359 aa) fasta scores: E(): 1.8e-50, 45.82% id in 371 aa.
      
 0.628
DIP0021
Similar to Streptomyces coelicolor probable solute-binding lipoprotein SC8F11.05 TR:Q9KZH3 (EMBL:AL353864) (340 aa) fasta scores: E(): 2.8e-63, 54.98% id in 331 aa.
      
 0.614
mshA
Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
  
 
 0.583
narH
Similar to Bacillus subtilis nitrate reductase beta chain NarH SW:NARH_BACSU (P42176) (487 aa) fasta scores: E(): 1.4e-114, 56.31% id in 499 aa.
      
 0.442
DIP0116
Putative membrane protein; Similar to Rhizobium loti MLR6622 protein TR:Q988S0 (EMBL:AP003009) (231 aa) fasta scores: E(): 1.4e-25, 40.99% id in 222 aa.
       0.424
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.