STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0117Putative lipase; Similar to Streptomyces coelicolor putative secreted lipase SCI11.24c TR:Q9S295 (EMBL:AL096849) (290 aa) fasta scores: E(): 6.8e-20, 33.18% id in 223 aa, and to Pseudomonas sp lipase precursor Lip SW:LIP_PSES5 (P25275) (364 aa) fasta scores: E(): 5.6e-05, 28.4% id in 176 aa. (260 aa)    
Predicted Functional Partners:
DIP0116
Putative membrane protein; Similar to Rhizobium loti MLR6622 protein TR:Q988S0 (EMBL:AP003009) (231 aa) fasta scores: E(): 1.4e-25, 40.99% id in 222 aa.
 
     0.602
DIP0118
Putative dehydrogenase; Similar to Thermus aquaticus NADH dehydrogenase Nox SW:NOX_THETH (Q60049) (205 aa) fasta scores: E(): 3.2e-07, 34.18% id in 196 aa.
       0.564
DIP0359
Putative secreted hydrolase; Low similarity to Streptomyces scabies esterase precursor EstA SW:ESTA_STRSC (P22266) (345 aa) fasta scores: E(): 0.12, 26.28% id in 331 aa.
  
   
 0.551
esxB
Very low similarity to Mycobacterium tuberculosis hypothetical 13.5 kDa protein Rv3445c or MTCY77.17c TR:O06262 (EMBL:Z95389) (125 aa) fasta scores: E(): 0.0007, 31.52% id in 92 aa; Belongs to the WXG100 family. CFP-10 subfamily.
  
     0.500
DIP1934
Hypothetical protein; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Streptomyces coelicolor putative secreted lipase SCD63A.10c TR:Q9KY65 (EMBL:AL356832) (331 aa) fasta scores: E(): 0.00018, 31.3% id in 214 aa, and Streptomyces coelicolor putative lipase 2SCG18.12c TR:Q9K3H5 (EMBL:AL390188) (289 aa) fasta scores: E(): 0.00064, 28.94% id in 190 aa.
  
   
 0.496
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
     0.479
DIP1889
Similar to Streptomyces coelicolor putative transcriptional regulator SC2G5.15C TR:Q9Z5A8 (EMBL:AL035478) (279 aa) fasta scores: E(): 9.5e-35, 44.89% id in 274 aa, and to Rhizobium meliloti putative transcription regulator protein SMC03015 TR:CAC45219 (EMBL:AL591784) (245 aa) fasta scores: E(): 0.012, 25.55% id in 227 aa.
  
     0.466
DIP2015
Putative exported lipase; Similar to Streptomyces coelicolor putative secreted protein SC10G8.24c TR:Q9L181 (EMBL:AL158057) (445 aa) fasta scores: E(): 7.7e-31, 35.363% id in 427 aa, and to Saccharopolyspora spinosa SpnM TR:Q9ALN4 (EMBL:AY007564) (320 aa) fasta scores: E(): 2.2e-23, 36.111% id in 288 aa, and to Candida albicans secretory lipase 5 Lip5 TR:Q9P8W0 (EMBL:AF191318) (463 aa) fasta scores: E(): 2.1e-17, 24.877% id in 406 aa.
  
  
 0.465
DIP1802
Similar to Halobacterium sp hypothetical protein VNG1407C TR:Q9HPZ1 (EMBL:AE005058) (132 aa) fasta scores: E(): 2.8e-09, 37.06% id in 116 aa, and to Pseudomonas aeruginosa hypothetical protein PA2801 TR:Q9I042 (EMBL:AE004707) (134 aa) fasta scores: E(): 4e-07, 35.38% id in 130 aa.
  
   
 0.457
DIP0606
Conserved hypothetical protein; Similar to Corynebacterium glutamicum hypothetical 31.3 kDa protein TR:Q93QX1 (EMBL:AF159510) (287 aa) fasta scores: E(): 3.9e-56, 51.52% id in 295 aa.
  
     0.455
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (42%) [HD]