STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0118Putative dehydrogenase; Similar to Thermus aquaticus NADH dehydrogenase Nox SW:NOX_THETH (Q60049) (205 aa) fasta scores: E(): 3.2e-07, 34.18% id in 196 aa. (192 aa)    
Predicted Functional Partners:
DIP1988
Hypothetical protein; No significant database matches to the full length CDS. N-terminus is similar to the N-terminal region of Streptomyces coelicolor insertion element IS110 hypothetical protein SC3C8.10 SW:YIS1_STRCO (P19780) (405 aa) fasta scores: E(): 8.1e-15, 42.33% id in 137 aa, and to Shigella flexneri putative transposase for IS110 S0128 TR:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 4.6e-14, 40.87% id in 137 aa.
 
  
 0.695
DIP0117
Putative lipase; Similar to Streptomyces coelicolor putative secreted lipase SCI11.24c TR:Q9S295 (EMBL:AL096849) (290 aa) fasta scores: E(): 6.8e-20, 33.18% id in 223 aa, and to Pseudomonas sp lipase precursor Lip SW:LIP_PSES5 (P25275) (364 aa) fasta scores: E(): 5.6e-05, 28.4% id in 176 aa.
       0.564
DIP2329
Conserved integral membrane protein; Weak but full length similarity to many eg. Clostridium acetobutylicum uncharacterized conserved membrane protein, YhgE B.subtilis ortholog CAC3589 SWALL:AAK81512 (EMBL:AE007855) (783 aa) fasta scores: E(): 1.6e-16, 23.62% id in 766 aa.
  
    0.448
DIP2190
Similar to Mycobacterium tuberculosis putative polyketide synthase FadD32 or Rv3801c or MT3908 or MTV026.06c TR:O53580 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.4e-78, 41.07% id in 616 aa, and to Myxococcus xanthus saframycin MX1 synthetase B SafB TR:Q50857 (EMBL:U24657) (1770 aa) fasta scores: E(): 7.7e-59, 37.52% id in 557 aa.
  
 
   0.443
DIP1299
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 27.4 kDa protein Rv1457c or MTV007.04c SWALL:O86349 (EMBL:AL021184) (261 aa) fasta scores: E(): 1.5e-31, 41.47% id in 258 aa, and to Mycobacterium smegmatis hypothetical 24.4 kDa protein SWALL:O87317 (EMBL:AF027770) (236 aa) fasta scores: E(): 1.1e-23, 37.55% id in 237 aa.
  
    0.431
DIP1989
Putative membrane protein; Weakly similar to Streptomyces coelicolor putative ABC transporter integral membrane protein SCC30.14 TR:Q9L007 (EMBL:AL352972) (238 aa) fasta scores: E(): 1.9e-11, 28.91% id in 249 aa, and to Bacillus cereus hypothetical protein YvfS TR:Q9L4F5 (EMBL:AJ243712) (239 aa) fasta scores: E(): 3.1e-08, 23.79% id in 248 aa.
  
    0.431
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.420
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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