STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0125Conserved hypothetical protein; Similar to the C-terminal region of Pseudomonas aeruginosa hypothetical protein PA4923 SW:YDC3_PSEAE (P48636) (195 aa) fasta scores: E(): 3.3e-27, 44.97% id in 189 aa. (361 aa)    
Predicted Functional Partners:
DIP0983
Conserved hypothetical protein; Similar in its N-terminal region to Corynebacterium glutamicum ORF2 protein TR:Q46063 (EMBL:X81379) (211 aa) fasta scores: E(): 2.5e-63, 76.66% id in 210 aa, and to Streptomyces coelicolor hypothetical 27.5 kDa protein SCP8.03 TR:Q9FBL8 (EMBL:AL390975) (252 aa) fasta scores: E(): 7.5e-60, 64.08% id in 245 aa; Belongs to the LOG family.
 
   
0.905
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
  
 0.870
miaB
Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
     
 0.863
DIP0654
Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.862
DIP0126
Similar to Streptomyces coelicolor conserved hypothetical protein SCBAC36F5.07 TR:CAC42843 (EMBL:AL592292) (562 aa) fasta scores: E(): 3.6e-40, 35.62% id in 553 aa.
       0.828
DIP0127
Similar to Streptomyces coelicolor putative regulatory protein SCE50.15 TR:Q9L048 (EMBL:AL163672) (168 aa) fasta scores: E(): 3.3e-18, 41.89% id in 148 aa.
       0.763
DIP0123
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 46.1 kDa protein Rv0485 or MT0503 or MTCY20G9.11 SW:Y485_MYCTU (Q11151) (438 aa) fasta scores: E(): 1.4e-12, 32.14% id in 224 aa.
       0.497
DIP0124
Putative membrane protein; Similar to Streptomyces coelicolor putative integral membrane protein SCBAC19F3.14 TR:CAC44337 (EMBL:AL596102) (517 aa) fasta scores: E(): 3.6e-47, 37.96% id in 453 aa.
       0.492
ftsH
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
    0.461
DIP0985
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 34.0 kDa protein SCD95A.25c TR:Q9KXU9 (EMBL:AL357432) (314 aa) fasta scores: E(): 2.9e-29, 47.67% id in 258 aa, and to Methanothermobacter thermautotrophicus dolichyl-phosphate mannose synthase related protein MTH374 TR:O26474 (EMBL:AE000823) (291 aa) fasta scores: E(): 1.4e-08, 31.89% id in 254 aa.
     
 0.411
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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