STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0149Conserved hypothetical protein (pseudogene); Pseudogene. Similar to the plasmid borne Corynebacterium striatum YtpG TR:Q9FB50 (EMBL:AF024666) (76 aa) fasta scores: E(): 3.2e-09, 78.46% id in 65 aa. Presents a frameshift at residue 50. (99 aa)    
Predicted Functional Partners:
DIP0151
Similar to Streptomyces coelicolor conserved hypothetical protein SC10F4.36c TR:Q9F3M5 (EMBL:AL450350) (94 aa) fasta scores: E(): 8.6e-07, 38.2% id in 89 aa, and to Mycobacterium tuberculosis hypothetical 11.0 kDa protein Rv3204 or MTCY07D11.22c TR:O05862 (EMBL:Z95120) (101 aa) fasta scores: E(): 0.00013, 40% id in 95 aa.
     
 0.873
DIP0150
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT0934.1 TR:AAK45182 (EMBL:AE006980) (257 aa) fasta scores: E(): 3.3e-32, 41.96% id in 255 aa.
       0.836
recF
DNA replication and repair protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
  
  
 0.768
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
  
  
 0.437
DIP0135
Similar to Mycobacterium tuberculosis putative oxidoreductase Rv0484c or MT0502 or MTCY20G9.10c SW:Y484_MYCTU (Q11150) (251 aa) fasta scores: E(): 1.2e-45, 57.32% id in 232 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.421
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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