STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
beta371Immunity-specific protein Beta371; Almost identical to previously sequenced Corynephage beta immunity-specific protein Beta371 beta371 TR:Q37922 (EMBL:L04258) (371 aa) fasta scores: E(): 9.9e-126, 89.75% id in 371 aa. (371 aa)    
Predicted Functional Partners:
beta201
Immunity-specific protein Beta201; Similar to the previously sequenced Corynephage beta immunity-specific protein Beta201 TR:Q37920 (EMBL:L04258) (201 aa) fasta scores: E(): 3.9e-64, 85.64% id in 202 aa. Note: there is a frameshift in the already sequenced data in from residue 167.
       0.842
beta286
Immunity-specific protein Beta286; Almost identical to previously sequenced Corynephage beta immunity-specific protein Beta286 TR:Q37921 (EMBL:L04258) (286 aa) fasta scores: E(): 1.1e-115, 99.65% id in 286 aa.
       0.842
DIP0212
Immunity-specific protein Beta241; C-terminal region identical to Corynephage beta immunity-specific protein Beta241 TR:Q37919 (EMBL:L04258) (241 aa) fasta scores: E(): 3.1e-64, 100% id in 241 aa, and whole length similar to Staphylococcus aureus subspaureus Mu50 phi pvl ORF15 and 16 homologue SAV1955 TR:BAB58117 (EMBL:AP003364) (1509 aa) fasta scores: E(): 2.9e-19, 23.76% id in 1073 aa.
       0.788
DIP0216
Putative phage tail fiber protein; Low similarity to N-terminal region of Bacteriophage lambda side tail fiber protein Stf SW:STF_LAMBD (P03764) (774 aa) fasta scores: E(): 0.0021, 24.28% id in 383 aa.
       0.773
DIP0217
Hypothetical protein; No significant database matches.
       0.773
DIP0211A
Hypothetical protein; No significant database matches.
       0.736
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.711
DIP2105
Putative exported protein; Similar to the N-terminal portion of many from actinomycetes eg. Streptomyces coelicolor putative secreted protein SCE41.06c TR:Q9F2Q2 (EMBL:AL442120) (244 aa) fasta scores: E(): 7.5e-21, 65.74% id in 108 aa. Also full length similarity to others from actinomycetes eg. Streptomyces coelicolor putative membrane protein SC5C11.15 TR:Q9L157 (EMBL:AL158060) (121 aa) fasta scores: E(): 1.9e-14, 50.49% id in 101 aa.
   
 
 0.613
DIP0219
Putative membrane protein; No significant database matches.
       0.556
DIP0220
Putative membrane protein; No significant database matches.
       0.556
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.