STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0236Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 1.2e-31, 42.802% id in 257 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.094, 27.559% id in 127 aa. Note: Also similar to DIP0233 (329 aa) E(): 5.2e-25; 45.031% identity in 322 aa overlap. Note: Also similar to DIP2012, DIP2224 and DIP2225. (312 aa)    
Predicted Functional Partners:
DIP0235
Putative fimbrial subunit; Similar to Actinomyces viscosus type-1 fimbrial major subunit precursor FimP TR:Q9X4D1 (EMBL:AF106034) (535 aa) fasta scores: E(): 6.9e-16, 31.5% id in 530 aa. Note: Contains a potential sortase anchor site (LTMPG) upstream of the C-terminal region transmembrane domain.
 
     0.888
DIP0238
Putative surface-anchored fimbrial subunit; Weak similarity to Actimomyces fimbrial associated protein. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain.
 
     0.887
DIP0237
Putative surface anchored protein; No significant database matches. Note: Contains a potential sortase anchor site (LALTG) upstream of the C-terminal region transmembrane domain.
       0.781
DIP2013
Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 4.4e-20, 28.827% id in 503 aa, and to Actinomyces naeslundii type-1 fimbrial major subunit precursor FimP TR:Q9X4D8 (EMBL:AF107019) (533 aa) fasta scores: E(): 8.5e-15, 27.432% id in 514 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
 
   
 0.781
DIP2226
Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 1e-30, 38.276% id in 580 aa, and to Actinomyces viscosus fimbrial subunit type 1 precursor SW:FM1_ACTVI (P18477) (533 aa) fasta scores: E(): 7.4e-12, 29.856% id in 556 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
 
     0.778
DIP2227
Probable surface-anchored fimbrial subunit; Similar to Actinomyces naeslundii hypothetical 103.4 kDa protein TR:Q9EV17 (EMBL:AJ401093) (976 aa) fasta scores: E(): 0.0003, 29.146% id in 597 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
  
    0.744
DIP0824
Putative folate reductase; Similar to Mycobacterium avium dihydrofolate reductase FolA TR:O30463 (EMBL:AF006616) (181 aa) fasta scores: E(): 2e-22, 46.1% id in 167 aa, and to Escherichia coli dihydrofolate reductase FolA or TmrA or B0048 SW:DYR_ECOLI (P00379) (159 aa) fasta scores: E(): 1.5e-13, 42.76% id in 152 aa.
      
 0.584
DIP0234
Hypothetical protein; No significant database matches.
       0.502
DIP2010
Similar to Actinomyces viscosus putative usher-like protein precursor TR:Q9AJ93 (EMBL:AF106034) (1411 aa) fasta scores: E(): 0.034, 22.657% id in 843 aa, and to Actinomyces naeslundii putative fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.14, 25.131% id in 191 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
  
     0.462
DIP2066
Some similarity to Actinomyces naeslundii putative fimbrial associated protein TR:O05995 (EMBL:U85708) (375 aa) fasta scores: E(): 0.0012, 28.803% id in 309 aa. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain.
  
     0.460
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.