STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gntPGluconate permease; Similar to Corynebacterium glutamicum gluconate permease GntP TR:Q9AL75 (EMBL:AJ296014) (463 aa) fasta scores: E(): 2.9e-113, 69.34% id in 460 aa, and to Bacillus subtilis gluconate permease GntP SW:GNTP_BACSU (P12012) (448 aa) fasta scores: E(): 4.8e-53, 38.58% id in 451 aa. (462 aa)    
Predicted Functional Partners:
DIP0515
Similar to Escherichia coli O157:H7 EDL933 putative transport protein Z1054 TR:AAG55204 (EMBL:AE005264) (512 aa) fasta scores: E(): 4.3e-19, 24% id in 479 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRDFFK) at the N-terminal region.
   
    0.744
glpF
Similar to Bacillus subtilis glycerol uptake facilitator protein GlpF SW:GLPF_BACSU (P18156) (274 aa) fasta scores: E(): 2.1e-23, 45.83% id in 240 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.712
gluQ
Putative glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
       0.554
tgt
Putative tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form [...]
       0.547
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
      
 0.494
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
      
 0.474
hemH
Putative ferrochelatase (protoheme biosynthesis); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
      
 0.460
DIP1746
Similar to Escherichia coli xylulose kinase XylB or B3564 SW:XYLB_ECOLI (P09099) (484 aa) fasta scores: E(): 6.8e-22, 30.57% id in 471 aa.
 
  
 0.442
DIP1548
Similar to Bacillus halodurans glycerate kinase GlxK or BH0555 SW:GRK_BACHD (Q9Z9P2) (380 aa) fasta scores: E(): 1e-29, 35.14% id in 350 aa, and to Bacillus subtilis glycerate kinase GlxK or S14A SW:GRK_BACSU (P42100) (382 aa) fasta scores: E(): 7.1e-28, 32.4% id in 395 aa, and to Escherichia coli glycerate kinase 1 GlxK or GlxB5 or B0514 SW:GRK1_ECOLI (P77364) (381 aa) fasta scores: E(): 7.6e-25, 33.93% id in 333 aa; Belongs to the glycerate kinase type-1 family.
 
  
 0.426
pyk
Pyruvate kinase; Similar to Corynebacterium glutamicum pyruvate kinase Pyk SW:KPYK_CORGL (Q46078) (475 aa) fasta scores: E(): 1.3e-146, 83.36% id in 469 aa, and to Bacillus psychrophilus pyruvate kinase Pyk SW:KPYK_BACPY (P51182) (586 aa) fasta scores: E(): 6.9e-64, 41.45% id in 480 aa.
     
 0.414
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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