STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP0256Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches. (48 aa)    
Predicted Functional Partners:
DIP1677
Putative ribonuclease (pseudogene and partial); Pseudogene. Similar to Rhizobium loti ribonuclease MLL0040 TR:Q98NP8 (EMBL:AP002994) blast scores: E(): 2e-06, score: 53 40% id, and to Bacillus subtilis ribonuclease R Rnr or VacB SW:RNR_BACSU (O32231) blast scores: E(): 1e-04, score: 47 43% id. Presents a frameshift at residue 82.
      
 0.618
DIP1678
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 39.8 kDa protein ML1637 or MLCB1243.38 TR:O69483 (EMBL:AL023635) (371 aa) fasta scores: E(): 1.8e-73, 54.61% id in 379 aa.
      
 0.618
DIP1679
Conserved hypothetical protein; Low similarity to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2229c or MT2288 or MTCY427.10c SW:YM29_MYCTU (Q10513) (245 aa) fasta scores: E(): 1.9e-06, 23.75% id in 240 aa.
      
 0.618
DIP0255
Hypothetical protein; Doubtful CDS. No strong consensus RBS usptream. No significant database matches.
       0.520
DIP0257
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3825 TR:AAK48194 (EMBL:AE007179) (435 aa) fasta scores: E(): 5.2e-94, 55.95% id in 420 aa.
       0.449
DIP0258
Hypothetical protein; No significant database matches.
       0.449
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.441
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.405
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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