Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP0260Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (106 aa)    
Predicted Functional Partners:
recR
Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
  
 0.990
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
  
 0.834
clpP2
ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.784
DIP1926
Putative prolyl oligopeptidase; Similar to Mycobacterium tuberculosis CDC1551 protease II MT0805 TR:AAK45047 (EMBL:AE006971) (718 aa) fasta scores: E(): 1.1e-159, 55.68% id in 695 aa, and to Mycobacterium leprae ML2226 TR:O05748 (EMBL:Z95151) (724 aa) fasta scores: E(): 8.2e-148, 52.36% id in 699 aa.
  
  
 0.755
DIP0729
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 49.4 kDa protein Rv3195 or MTV014.39 TR:O53341 (EMBL:AL021646) (472 aa) fasta scores: E(): 5.1e-65, 45.37% id in 432 aa.
   
  
 0.747
DIP0257
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3825 TR:AAK48194 (EMBL:AE007179) (435 aa) fasta scores: E(): 5.2e-94, 55.95% id in 420 aa.
       0.689
DIP0258
Hypothetical protein; No significant database matches.
       0.689
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
    0.415
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
 
    0.401
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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