STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0276Putative membrane protein; Similar to Corynebacterium glutamicum hypothetical 29.6 kDa protein in leuA-lysC intergenic region SW:YLEU_CORGL (P42459) (270 aa) fasta scores: E(): 4.6e-47, 58.18% id in 220 aa. (278 aa)    
Predicted Functional Partners:
DIP0263
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 43.4 kDa protein Rv3712 or MTV025.060 TR:O69679 (EMBL:AL022121) (413 aa) fasta scores: E(): 2.3e-86, 59.95% id in 412 aa, and to Streptomyces coelicolor putative ligase 2SCG58.12 TR:Q9FCA1 (EMBL:AL391017) (412 aa) fasta scores: E(): 4.3e-59, 43.03% id in 409 aa.
 
     0.715
DIP0262
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 cobyric acid synthase MT3816 TR:AAK48185 (EMBL:AE007178) (231 aa) fasta scores: E(): 1.3e-31, 58.13% id in 246 aa, and to Streptomyces coelicolor hypothetical 26.2 kDa protein 2SCG58.13 TR:Q9FCA0 (EMBL:AL391017) (242 aa) fasta scores: E(): 6.6e-20, 42.85% id in 252 aa.
 
     0.673
lysC
Aspartokinase; Similar to Corynebacterium flavum aspartokinase LysC or Ask SW:AK_CORFL (P41398) (421 aa) fasta scores: E(): 1.8e-135, 87.64% id in 421 aa; Belongs to the aspartokinase family.
     
 0.671
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.661
DIP0361
Putative bifunctional protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
  
 0.634
uvrD
Putative DNA helicase II; Similar to Mycobacterium tuberculosis probable DNA helicase II homolog UvrD or Rv3198c or MT3291 or MTV014.42c SW:UVRD_MYCTU (O53344) (700 aa) fasta scores: E(): 2.7e-133, 58.92% id in 689 aa, and to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or RecL or B3813 SW:UVRD_ECOLI (P03018) (720 aa) fasta scores: E(): 7.8e-37, 32.16% id in 656 aa.
    
 
 0.626
DIP0264
Putative helicase; Similar to Mycobacterium tuberculosis CDC1551 DNA polymerase III, epsilon subunit MT3814 TR:AAK48182 (EMBL:AE007178) (329 aa) fasta scores: E(): 1.3e-07, 25.37% id in 335 aa, and to Bacillus subtilis probable ATP-dependent helicase DinG homolog SW:DING_BACSU (P54394) (931 aa) fasta scores: E(): 0.48, 24.07% id in 108 aa.
 
 
   0.611
DIP2281
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 44.0 kDa protein SC4G6.31c SWALL:Q9S2S7 (EMBL:AL096884) (403 aa) fasta scores: E(): 4.6e-09, 25.49% id in 459 aa.
  
 
   0.566
DIP2009
Putative peptide synthase; N-terminal region similar to C-terminal region of Streptomyces lavendulae peptide synthetase SWALL:AAK81825 (EMBL:AF386507) (1531 aa) fasta scores: E(): 1.3e-38, 34.02% id in 814 aa, similar in its full length to Agrobacterium tumefaciens StrC58 AGR_l_3476p SWALL:AAK90311 (EMBL:AE008376) (1344 aa) fasta scores: E(): 6.2e-36, 32.96% id in 1338 aa, and N-terminal region similar to the full length of Amycolatopsis orientalis PCZA361.18 SWALL:O52803 (EMBL:AJ223998) (580 aa) fasta scores: E(): 1.3e-33, 38.2% id in 589 aa. C-terminal region presents low similarity [...]
 
  
 0.541
DIP1978
Putative exported protein; Similar to Mycobacterium tuberculosis hypothetical protein Rv3587c TR:O53572 (EMBL:AL022075) (264 aa) fasta scores: E(): 2.9e-10, 29.13% id in 230 aa, and to Mycobacterium leprae hypothetical membrane protein ML1918 TR:Q9CBJ2 (EMBL:AL583923) (263 aa) fasta scores: E(): 1e-08, 28.69% id in 230 aa.
  
     0.532
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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