STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigCSimilar to Mycobacterium tuberculosis probable RNA polymerase sigma-C factor SigC or Rv2069 or MT2129 or MTCY49.08 SW:RPSC_MYCTU (Q10679) (185 aa) fasta scores: E(): 6.1e-30, 52.24% id in 178 aa; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)    
Predicted Functional Partners:
DIP0577
Putative RNA-polymerase sigma factor; Similar to Mycobacterium tuberculosis probable RNA polymerase sigma-D factor SigD or Rv3414c or MT3523 or MTCY78.15 SW:RPSD_MYCTU (Q50712) (212 aa) fasta scores: E(): 7e-28, 48.58% id in 177 aa, and to Streptomyces coelicolor RNA polymerase sigma-E factor SigE or SCE94.07 SW:RPOE_STRCO (P38133) (176 aa) fasta scores: E(): 0.0002, 28.38% id in 155 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.877
cat
Catalase; Similar to Onchocerca volvulus endobacterium catalase Cat SW:CATA_ONCVE (Q27710) (482 aa) fasta scores: E(): 8e-92, 52.24% id in 490 aa.
     
 0.872
sigB
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
  
 0.838
DIP2372
Similar to Pseudomonas fluorescens alternative sigma factor AlgU TR:AAK94006 (EMBL:AF399758) (193 aa) fasta scores: E(): 8.1e-12, 30.1% id in 186 aa, and to Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU or AlgT or PA0762 SW:RPSH_PSEAE (Q06198) (193 aa) fasta scores: E(): 1.8e-11, 29.03% id in 186 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.836
rpoE
Similar to Mycobacterium tuberculosis RNA polymerase sigma-E factor RpoE or SigH or Rv3223c or MT3320 or MTCY07D11.03 SW:RPOE_MYCTU (O05843) (216 aa) fasta scores: E(): 1e-44, 70.33% id in 182 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
0.676
DIP0710
Similar to Streptomyces coelicolor anti-sigma factor RsrA TR:Q9RL96 (EMBL:AJ010320) (105 aa) fasta scores: E(): 5.5e-06, 35.71% id in 70 aa.
  
 
 0.597
DIP0995
Similar to Mycobacterium leprae hypothetical protein ML1077 TR:Q9CCA5 (EMBL:AL583920) (139 aa) fasta scores: E(): 8e-09, 40.35% id in 114 aa.
 
   0.526
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.514
DIP0880
Similar to Xanthomonas campestris probable RNA polymerase sigma factor RfaY SW:RFAY_XANCP (P46358) (217 aa) fasta scores: E(): 9.8e-07, 32.88% id in 149 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.499
DIP0099
Similar to Streptomyces coelicolor putative RNA polymerase sigma factor SCI11.12c TR:Q9S2A7 (EMBL:AL096849) (185 aa) fasta scores: E(): 2.8e-25, 47.36% id in 171 aa, and to Bacillus subtilis RNA polymerase sigma factor SigW SW:SIGW_BACSU (Q45585) (187 aa) fasta scores: E(): 3.9e-10, 31.39% id in 172 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
0.497
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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