STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0286Two-component regulatory protein; Similar to Klebsiella pneumoniae phosphate regulon transcriptional regulatory protein PhoB SW:PHOB_KLEPN (P45605) (229 aa) fasta scores: E(): 1.7e-25, 40.708% id in 226 aa, to Shigella dysenteriae phosphate regulon transcriptional regulatory protein PhoB SW:PHOB_SHIDY (P45606) (229 aa) fasta scores: E(): 6.5e-25, 40.265% id in 226 aa, and to Escherichia coli phosphate regulon transcriptional regulatory protein PhoB or B0399 or Z0497 or ECS0449 SW:PHOB_ECOLI (P08402) (229 aa) fasta scores: E(): 6.5e-25, 40.265% id in 226 aa. (233 aa)    
Predicted Functional Partners:
DIP0287
Similar to Escherichia coli sensor protein RcsC or B2218 SW:RCSC_ECOLI (P14376) (933 aa) fasta scores: E(): 5.5e-10, 26.339% id in 224 aa, and to Pseudomonas syringae sensor protein GacS or LemA SW:GACS_PSESY (P48027) (907 aa) fasta scores: E(): 2e-09, 27.530% id in 247 aa.
 
 
 0.966
mtrB
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis MtrB or Rv3245c or MTCY20B11.20c TR:O05890 (EMBL:Z95121) (567 aa) fasta scores: E(): 4.6e-89, 53.73% id in 482 aa, and to Streptomyces coelicolor sensor protein AfsQ2 or 2SCK8.32c SW:AFQ2_STRCO (Q04943) (535 aa) fasta scores: E(): 1.4e-23, 30.64% id in 447 aa.
 
 
 0.903
DIP0390
Putative two component system sensor kinase; Similar to Mycobacterium tuberculosis sensor-like histidine kinase SenX3 or Rv0490 or MT0509 or MTCY20G9.16 SW:SEX3_MYCTU (Q11155) (410 aa) fasta scores: E(): 3.6e-60, 48.84% id in 389 aa.
 
 
 0.880
DIP1935
Putative two somponent system sensor kinase protein; C-terminal region is similar to Mycobacterium tuberculosis hypothetical protein Rv0758 TR:P71815 (EMBL:Z80226) (485 aa) fasta scores: E(): 7.7e-38, 42.88% id in 471 aa, and to Bacillus halodurans two-component sensor histidine kinase BH0373 TR:Q9KFU8 (EMBL:AP001508) (459 aa) fasta scores: E(): 3.7e-29, 30.81% id in 464 aa.
 
 
 0.876
DIP0855
Putative two component system sensor kinase; Similar to Corynebacterium glutamicum sensor kinase TR:Q9F160 (EMBL:AF119221) (455 aa) fasta scores: E(): 6.5e-71, 46.98% id in 447 aa, and to Burkholderia pseudomallei sensor protein IrlS SW:IRLS_BURPS (O31396) (464 aa) fasta scores: E(): 4.6e-18, 26% id in 446 aa.
 
 
 0.796
DIP0063
Putative two-component system sensor protein; Similar to Escherichia coli sensor protein BaeS or B2078 SW:BAES_ECOLI (P30847) (467 aa) fasta scores: E(): 1.8e-28, 33.333% id in 372 aa.
 
 
 0.773
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.685
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.684
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.682
DIP0293
Putative Na+/H+ antiporter subunit; Similar to Pseudomonas aeruginosa probable NADH dehydrogenase PA1054 TR:Q9I4S0 (EMBL:AE004537) (933 aa) fasta scores: E(): 3e-85, 34.395% id in 942 aa, and to Rhizobium meliloti pH adaptation potassium efflux system transmembrane protein TR:CAC47489 (EMBL:AL591792) (999 aa) fasta scores: E(): 5.9e-61, 31.818% id in 968 aa, and to Staphylococcus aureus Na+/H+ antiporter subunit MnhA TR:Q9ZNG6 (EMBL:AB015981) (801 aa) fasta scores: E(): 6.5e-33, 31.750% id in 800 aa.
   
 
 0.609
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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