Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP0293Putative Na+/H+ antiporter subunit; Similar to Pseudomonas aeruginosa probable NADH dehydrogenase PA1054 TR:Q9I4S0 (EMBL:AE004537) (933 aa) fasta scores: E(): 3e-85, 34.395% id in 942 aa, and to Rhizobium meliloti pH adaptation potassium efflux system transmembrane protein TR:CAC47489 (EMBL:AL591792) (999 aa) fasta scores: E(): 5.9e-61, 31.818% id in 968 aa, and to Staphylococcus aureus Na+/H+ antiporter subunit MnhA TR:Q9ZNG6 (EMBL:AB015981) (801 aa) fasta scores: E(): 6.5e-33, 31.750% id in 800 aa. (970 aa)    
Predicted Functional Partners:
DIP0288
Putative membrane protein; No significant database matches.
  
 
 0.999
DIP0290
Similar to Vibrio cholerae hypothetical protein VCA0154 TR:Q9KN12 (EMBL:AE004356) (158 aa) fasta scores: E(): 0.0029, 30.588% id in 85 aa.
 
 
 0.999
DIP0291
Similar to Staphylococcus aureus Na+/H+-antiporter subunit MnhD or SA0810 TR:Q9ZNG3 (EMBL:AB015981) (498 aa) fasta scores: E(): 2.4e-35, 29.482% id in 502 aa.
 
 
0.999
DIP0292
Similar to Staphylococcus aureus Na+/H+-antiporter subunit MnhC or SA0811 TR:Q9ZNG4 (EMBL:AB015981) (113 aa) fasta scores: E(): 6.5e-08, 38.889% id in 90 aa.
 
 
 0.999
DIP0289
Putative membrane protein; No significant database matches.
  
 
 0.998
qcrB
Ubiquinol-cytochrome C reductase cytochrome B subunit; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
  
 
 0.789
DIP1750
Similar to Vibrio cholerae glutathione-regulated potassium-efflux system protein KefB, putative VC0992 TR:Q9KTB1 (EMBL:AE004180) (528 aa) fasta scores: E(): 1.3e-37, 33.26% id in 514 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.780
ctaE
Similar to Corynebacterium glutamicum cytochrome AA3 oxidase subunit III CtaE TR:Q9AEL8 (EMBL:AJ306418) (205 aa) fasta scores: E(): 9.9e-67, 81.95% id in 205 aa, and to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide III CtaE or Rv2193 or MT2249 or MTCY190.04 SW:COX3_MYCTU (Q10385) (203 aa) fasta scores: E(): 3.6e-47, 60% id in 205 aa.
   
 
 0.759
DIP0997
Putative ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   
 0.754
ctaD
Cytochrome C oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).
   
 
 0.749
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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