STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0298Putative penicillin-binding secreted protein; Similar to Mycobacterium leprae Pbp1 Pon1 SWALL:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 4.9e-130, 48.08% id in 757 aa, and to Mycobacterium tuberculosis CDC1551 penicillin-binding protein 1 MT3784 TR:AAK48151 (EMBL:AE007176) (810 aa) fasta scores: E(): 4.8e-134, 48.75% id in 761 aa. (794 aa)    
Predicted Functional Partners:
pbpA
Similar to Mycobacterium leprae putative penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa.
  
 
 
 0.863
DIP1497
Putative secreted penicillin-binding protein; Similar to Mycobacterium tuberculosis penecillin binding protein Rv2864c or MTV003.10c TR:O33346 (EMBL:AL008883) (603 aa) fasta scores: E(): 1.9e-81, 42.81% id in 612 aa, and to Staphylococcus aureus beta-lactam-inducible penicillin-binding protein Pbp SW:PBP_STAAU (P07944) (670 aa) fasta scores: E(): 2.3e-07, 21.04% id in 632 aa.
  
 
 
 0.855
ftsI
Putative penicillin-binding (cell division related) protein; Similar to Corynebacterium glutamicum penicillin-binding protein FtsI TR:Q9FAD4 (EMBL:AB041009) (704 aa) fasta scores: E(): 3.1e-122, 59.38% id in 677 aa, and to Streptomyces coelicolor FtsI TR:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 2e-42, 32.24% id in 611 aa.
  
 
 
 0.723
DIP1599
Putative cell division protein; Similar to Corynebacterium glutamicum FtsW protein TR:Q9L4H4 (EMBL:AJ242646) (490 aa) fasta scores: E(): 9.6e-78, 48.85% id in 481 aa, and to Escherichia coli cell division protein FtsW or B0089 or Z0099 or ECS0093 SW:FTSW_ECOLI (P16457) (414 aa) fasta scores: E(): 1e-21, 32.53% id in 375 aa; Belongs to the SEDS family.
  
 
 
 0.721
ag84
Antigen 84; Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three putative colied-coil regions (residues 84..131, 193..235, 248..273).
 
 
 
 0.706
repA
Putative IS element transposase (pseudogene); Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri putative transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor putative IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180.
    
 
 0.700
DIP1546
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.0 kDa protein Rv2927c or MT2997 or MTCY338.16c SW:YT27_MYCTU (Q10973) (245 aa) fasta scores: E(): 9e-21, 47.89% id in 238 aa.
 
 
 
 0.668
whiB
Putative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
       0.666
mltG
Putative secreted protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
   
 0.653
DIP0300
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 6.1 kDa protein SCH17.10c TR:Q9XA37 (EMBL:AL079353) (53 aa) fasta scores: E(): 5.4e-16, 85.71% id in 49 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3780 TR:AAK48147 (EMBL:AE007175) (53 aa) fasta scores: E(): 5.9e-14, 77.08% id in 48 aa.
       0.616
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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