STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiBPutative regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (115 aa)    
Predicted Functional Partners:
DIP0300
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 6.1 kDa protein SCH17.10c TR:Q9XA37 (EMBL:AL079353) (53 aa) fasta scores: E(): 5.4e-16, 85.71% id in 49 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3780 TR:AAK48147 (EMBL:AE007175) (53 aa) fasta scores: E(): 5.9e-14, 77.08% id in 48 aa.
       0.757
DIP0301
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3779 TR:AAK48146 (EMBL:AE007175) (151 aa) fasta scores: E(): 1.3e-30, 63.75% id in 149 aa, and to Streptomyces coelicolor hypothetical 15.7 kDa protein SCH17.09c TR:Q9XA38 (EMBL:AL079353) (155 aa) fasta scores: E(): 2.5e-29, 62.25% id in 151 aa.
       0.757
putP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
    0.745
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.744
DIP1514
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 12.2 kDa protein Rv2901c or MT2969 or MTCY274.32c SW:YT01_MYCTU (Q10822) (101 aa) fasta scores: E(): 3.7e-31, 70.29% id in 101 aa, and to Streptomyces coelicolor hypothetical 12.3 kDa protein SC2E1.18 TR:O69889 (EMBL:AL023797) (102 aa) fasta scores: E(): 2.9e-27, 67% id in 100 aa.
  
     0.711
secG
Protein transport/translocation membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
 
     0.697
DIP1207
Putative transcriptional regulator; Similar to Mycobacterium tuberculosis hypothetical 24.0 kDa protein Rv1830 or MT1879 or MTCY1A11.13c SWALL:YI30_MYCTU (SWALL:Q50603) (225 aa) fasta scores: E(): 1.5e-41, 72.98% id in 174 aa, and to Bacillus subtilis regulatory protein GlnR SWALL:GLNR_BACSU (SWALL:P37582) (135 aa) fasta scores: E(): 0.22, 29.16% id in 72 aa.
  
     0.693
DIP0302
Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase Rv3677c or MTV025.025c TR:O69645 (EMBL:AL022121) (264 aa) fasta scores: E(): 1.1e-18, 40.89% id in 269 aa.
       0.677
DIP0298
Putative penicillin-binding secreted protein; Similar to Mycobacterium leprae Pbp1 Pon1 SWALL:P72351 (EMBL:S82044) (821 aa) fasta scores: E(): 4.9e-130, 48.08% id in 757 aa, and to Mycobacterium tuberculosis CDC1551 penicillin-binding protein 1 MT3784 TR:AAK48151 (EMBL:AE007176) (810 aa) fasta scores: E(): 4.8e-134, 48.75% id in 761 aa.
       0.666
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.624
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.