STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP0313Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 36.7 kDa protein Rv3659c or MTV025.007c TR:O69627 (EMBL:AL022121) (352 aa) fasta scores: E(): 6.7e-51, 52.21% id in 316 aa. (365 aa)    
Predicted Functional Partners:
DIP0314
Putative membrane protein; Similar to Mycobacterium tuberculosis putative transmembrane protein Rv3658c or MTV025.006c TR:O69626 (EMBL:AL022121) (266 aa) fasta scores: E(): 6.1e-17, 36.52% id in 230 aa.
  
  
 0.938
DIP0315
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 19.1 kDa protein Rv3657c or MTV025.005c TR:O69625 (EMBL:AL022121) (191 aa) fasta scores: E(): 2.9e-10, 36.66% id in 150 aa.
  
  
 0.938
DIP0316
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 7.1 kDa protein Rv3656c or MTV025.004c TR:O69624 (EMBL:AL022121) (68 aa) fasta scores: E(): 2.6e-05, 43.33% id in 60 aa.
     
 0.888
DIP0312
Putative morphological differentiation-related protein; Similar to Mycobacterium tuberculosis hypothetical 35.8 kDa protein Rv3660c or MT3760 or MTV25.008c TR:O69628 (EMBL:AL022121) (350 aa) fasta scores: E(): 9.7e-19, 30.29% id in 340 aa, and to Streptomyces cyaneus (Streptomyces curacoi) inhibition of morphological differentiation TR:O33612 (EMBL:AB004855) (370 aa) fasta scores: E(): 1.6e-13, 33.08% id in 266 aa.
       0.842
DIP0318
Putative secreted protein; Similar to the central region of Streptomyces coelicolor membrane spanning protein SCH5.14c TR:Q9X916 (EMBL:AL035636) (230 aa) fasta scores: E(): 2.6e-05, 35.23% id in 105 aa.
     
 0.807
DIP0317
Putative secreted protein; Similar to Mycobacterium tuberculosis hypothetical 13.0 kDa protein Rv3655c or MTV025.003c TR:O69623 (EMBL:AL022121) (125 aa) fasta scores: E(): 1.4, 31.81% id in 66 aa.
       0.794
DIP0860
Putative membrane protein; No significant database matches.
  
  
 0.494
lexA
Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
     0.400
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.