Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DIP0357C-terminal region Similar to Deinococcus radiodurans alpha-dextran endo-1,6-alpha-glucosidase DR0405 TR:Q9RXB0 (EMBL:AE001900) (910 aa) fasta scores: E(): 3.1e-110, 41.4% id in 942 aa, and N-terminal region similar to Streptomyces lividans alpha-amylase precursor Amy SW:AMY_STRLI (Q05884) (919 aa) fasta scores: E(): 1.4e-86, 41.56% id in 676 aa; Belongs to the glycosyl hydrolase 13 family. (2578 aa)    
Predicted Functional Partners:
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.869
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
  
 0.858
DIP1552
Putative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.846
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
  
 0.825
DIP0153
Hypothetical protein; No significant database matches.
  
 
 0.744
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
  
  
 0.720
DIP0353
Putative exported protein; Similar to N-terminal region of Streptococcus pneumoniae 3-hydroxy-3-methylglutaryl-CoA reductase SP1726 TR:AAK75803 (EMBL:AE007465) (424 aa) fasta scores: E(): 8.7, 26.38% id in 144 aa.
      
 0.618
DIP0358
Putative CoA-ligase; Similar to Mycobacterium tuberculosis CDC1551 substrate--CoA ligase, putative MT1470 TR:AAK45735 (EMBL:AE007017) (535 aa) fasta scores: E(): 8.6e-57, 36.1% id in 529 aa.
      
 0.618
DIP1726
Putative glucanotransferase; Similar to Mycobacterium tuberculosis 4-alpha-glucanotransferase MalQ or Rv1781c or MT1831 or MTV049.03c SW:MALQ_MYCTU (O53932) (724 aa) fasta scores: E(): 7.8e-73, 45.87% id in 728 aa, and to Escherichia coli 4-alpha-glucanotransferase MalQ or MalA or B3416 SW:MALQ_ECOLI (P15977) (694 aa) fasta scores: E(): 1.2e-29, 28.48% id in 660 aa.
  
  
 0.606
DIP0534
Putative sugar-binding secreted protein; Similar to Lactococcus lactis maltose ABC transporter substrate binding protein MalE TR:Q9CEZ8 (EMBL:AE006399) (410 aa) fasta scores: E(): 8.8e-35, 33.66% id in 407 aa.
 
  
 0.555
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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