STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rmlBSimilar to Mycobacterium leprae putative dTDP-(glucose or rhamnose)-4,6-dehydratase RmlB TR:Q9X7A3 (EMBL:AL049491) (331 aa) fasta scores: E(): 8.3e-84, 63.77% id in 334 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (335 aa)    
Predicted Functional Partners:
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 
 0.999
DIP0361
Putative bifunctional protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
 
 0.999
DIP2141
Similar to Streptomyces coelicolor putative UDP-glucose 6-dehydrogenase SCBAC19G2.07 TR:CAC44517 (EMBL:AL596138) (447 aa) fasta scores: E(): 2.8e-33, 40.75% id in 422 aa, and to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or pa2022 SW:UDG_PSEAE (O86422) (453 aa) fasta scores: E(): 1.9e-26, 39.66% id in 358 aa, and to Rhizobium meliloti UDP-glucose 6-dehydrogenase Rkpk or r01082 or smc02641 SW:UDG_RHIME (O54068) (437 aa) fasta scores: E(): 8.9e-26, 37.71% id in 411 aa, and to Escherichia coli UDP-glucose 6-dehydrogenase KfiD SW:UDG5_ECOLI (Q47329) (392 aa) fasta scores: E(): [...]
 
  
 0.881
DIP0363
Similar to Streptomyces coelicolor putative metallopeptidase SCD95A.06c TR:Q9KXW8 (EMBL:AL357432) (473 aa) fasta scores: E(): 5.2e-42, 32.16% id in 457 aa.
       0.836
DIP0364
Similar to Mycobacterium tuberculosis CDC1551 prolyl oligopeptidase family protein MT0473 TR:AAK44697 (EMBL:AE006950) (673 aa) fasta scores: E(): 9.6e-118, 46.64% id in 671 aa.
       0.836
glf
Similar to Escherichia coli UDP-galactopyranose mutase Glf or B2036 SW:GLF_ECOLI (P37747) (367 aa) fasta scores: E(): 5.4e-48, 45.35% id in 377 aa, and to Mycobacterium tuberculosis UDP-galactopyranose mutase Glf or Rv3809c or MTV026.14 TR:O06934 (EMBL:U96128) (399 aa) fasta scores: E(): 1.3e-121, 76.09% id in 389 aa.
  
  
 0.829
slpA
Surface layer protein A; Similar to Corynebacterium ammoniagenes surface layer protein A SlpA TR:BAB62413 (EMBL:AB055224) (358 aa) fasta scores: E(): 1.4e-69, 52.76% id in 362 aa, and to Mycobacterium tuberculosis antigen 85-A precursor FbpA or MPT44 or Rv3804c or MT3911 or MTV026.09c SW:A85A_MYCTU (P17944) (338 aa) fasta scores: E(): 9.7e-18, 31.56% id in 320 aa.
       0.681
galE
UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
 
  
0.659
DIP0681
Putative glycosyl transferase; Similar to Mycobacterium tuberculosis CDC1551 glycosyl transferase MT3365 TR:AAK47706 (EMBL:AE007146) (301 aa) fasta scores: E(): 5.1e-56, 52.12% id in 282 aa.
 
  
 0.640
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
      0.606
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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