Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pflBHMMPfam hit to PF02901, Pyruvate formate lyase. (270 aa)    
Predicted Functional Partners:
DIP0383
Conserved hypothetical protein; Low similarity to Mycobacterium tuberculosis hypothetical 19.1 kDa protein Rv0481c or MT0499 or MTCY20G9.07c SW:Y481_MYCTU (Q11147) (174 aa) fasta scores: E(): 0.028, 23.92% id in 163 aa.
 
     0.838
DIP0553
Putative membrane protein; Low similarity to Streptomyces coelicolor putative membrane protein SCl2.30c TR:Q9L269 (EMBL:AL137778) (150 aa) fasta scores: E(): 1.9e-06, 35.48% id in 93 aa.
  
     0.702
murB
Putative peptidoglycan synthesis related protein; Cell wall formation.
       0.681
DIP0363
Similar to Streptomyces coelicolor putative metallopeptidase SCD95A.06c TR:Q9KXW8 (EMBL:AL357432) (473 aa) fasta scores: E(): 5.2e-42, 32.16% id in 457 aa.
  
     0.517
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
     0.495
DIP1849
Putative membrane protein; Similar to Mycobacterium leprae hypothetical protein ML1176 (P54133) (119 aa) fasta scores: E(): 3.7e-09, 39.28% id in 112 aa, and to Mycobacterium tuberculosis hypothetical protein Rv1342c SW:YD42_MYCTU (Q11012) (120 aa) fasta scores: E(): 1.5e-08, 37.16% id in 113 aa.
  
     0.455
DIP1614
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv2175c or MTV021.08c TR:O53509 (EMBL:AL021957) (146 aa) fasta scores: E(): 7.8e-08, 40.45% id in 131 aa.
  
     0.434
DIP2009
Putative peptide synthase; N-terminal region similar to C-terminal region of Streptomyces lavendulae peptide synthetase SWALL:AAK81825 (EMBL:AF386507) (1531 aa) fasta scores: E(): 1.3e-38, 34.02% id in 814 aa, similar in its full length to Agrobacterium tumefaciens StrC58 AGR_l_3476p SWALL:AAK90311 (EMBL:AE008376) (1344 aa) fasta scores: E(): 6.2e-36, 32.96% id in 1338 aa, and N-terminal region similar to the full length of Amycolatopsis orientalis PCZA361.18 SWALL:O52803 (EMBL:AJ223998) (580 aa) fasta scores: E(): 1.3e-33, 38.2% id in 589 aa. C-terminal region presents low similarity [...]
 
  
 0.417
DIP2040
Putative membrane protein; Similar to Mycobacterium leprae probable conserved membrane protein ML1504 SWALL:Q9CBX0 (EMBL:AL583922) (430 aa) fasta scores: E(): 1.8e-10, 31.8% id in 349 aa, and to Mycobacterium tuberculosis hypothetical 47.1 kDa protein Rv1159 or MT1195 or MTCI65.26 SWALL:O06557 (EMBL:Z95584) (431 aa) fasta scores: E(): 4.3e-10, 31.66% id in 360 aa.
  
     0.412
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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